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EAN 2023

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Jul 3 / Roche and Genentech
ILLUMINATE: A Real-World Study Assessing Usability and Value of Integrated Digital Tools for MS care
A study design report for the ILLUMINATE study, a non-interventional proof-of-concept study assessing the usability and value of a digital MS care management platform in medical practice. The ILLUMINATE study design, rationale and aim, study objectives and their corresponding endpoints are presented.

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Jul 2 / Roche and Genentech
Attitudes toward seeking professional help among patients with early alzheimer´s disease
An earlier diagnosis of Alzheimer's disease (AD) allows patients and their families to be better informed to make decisions and plan their lives, benefit from pharmacological and non-pharmacological strategies, and have the possibility to participate in clinical trials of new diseasemodifying agents. Knowledge of the active process of seeking professional help in the early stages of AD and its associated factors is still limited. The aim of this study was to assess the phenomenon.

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Jul 2 / Roche and Genentech
Efficacy and Safety of Fenebrutinib, a Noncovalent, Reversible BTK inhibitor, in MS: Primary Results of a Phase 2 Trial
Bruton’s tyrosine kinase (BTK) is implicated in peripheral and central nervous system inflammation in multiple sclerosis (MS) and is a therapeutic target for relapsing and progressive disease. Fenebrutinib is a potent, highly selective, noncovalent, reversible BTK inhibitor under investigation for MS. The objective of FENopta, a randomized, double-blind, placebo-controlled, Phase 2 trial (NCT05119569), was to evaluate efficacy and safety of fenebrutinib in relapsing MS.
02:00 PM
Duration 5mins ePoster area
FIREFISH Parts 1 and 2: 48-month efficacy and safety of risdiplam▼ in Type 1 spinal muscular atrophy (SMA)
M Mazurkiewicz-Beldzinska, G Baranello, O Boespflug-Tanguy, JW Day, N Deconinck, A Klein, R Masson, E Mercuri, K Rose, L Servais, D Vlodavets, H Xiong, E Zanoteli, M El-Khairi, M Gerber, K Gorni, H Kletzl, L Palfreeman, A Dodman, BT Darras

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Duration 5mins ePoster area
SUNFISH Parts 1 and 2: 4-year efficacy and safety data of risdiplam▼ in Types 2 and 3 spinal muscular atrophy (SMA)
A Kostera-Pruszczyk, JW Day, N Deconinck, ES Mazzone, A Nascimento, M Oskoui, K Saito, C Vuillerot, G Baranello, O Boespflug-Tanguy, N Goemans, J Kirschner, L Servais, J Braid, M Gerber, K Gorni, C Martin, WY Yeung, RS Scalco, E Mercuri

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