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Acute Myeloid Leukemia

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Dec 7 / Roche and Genentech
Incorporating Patient-Reported Outcomes Version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE) into Dose Review in a Phase I Clinical Trial
Adverse event information from the Common Terminology Criteria for Adverse Events (CTCAE) and the Patient-Reported Outcomes version of the CTCAE was incorporated into a dose review report from a Phase I trial of patients with relapsed/refractory acute myeloid leukemia. Results from the final dose review report in a cohort of four patients, including feedback on the report, are presented.

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Jul 4 / Roche and Genentech
Real-World Treatment Experience of Venetoclax in Combination with Hypomethylating Agents in Patients with Newly Diagnosed Acute Myeloid Leukemia: Updated Experience from a Predominantly Community Setting in the US
A retrospective cohort study using the Flatiron Health electronic health record-derived, nationwide, de-identified database to better understand the real-world treatment experience of Ven+HMA in routine clinical care pre- and post-VIALE-A in patients with newly diagnosed acute myeloid leukemia.

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Jul 7 / Roche and Genentech
Clinical Evaluation of Somatic Genomic Alteration Annotation for Hematological Malignancies using NAVIFY® Tertiary Analysis Software
The NAVIFY® Mutation Profiler is a CE-marked, cloud-based tertiary analysis software that provides curation, annotation, and reporting of somatic genomic alterations and biomarker signatures identified by NGS (next-generation sequencing). This poster shows the results of a clinical evaluation study validating the accuracy and reproducibility of the NMP software and curation process across a panel of hematologic malignancies.

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