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Macula Society 2025

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Feb 21 / Roche and Genentech
Impact of Early Intraretinal Fluid Reduction on One-Year Outcomes in Diabetic Macular Edema
This presentation describes an analysis investigating the relationship between the reduction in intraretinal fluid volume after 3 months of treatment and 2-year anatomic and visual outcomes in patients with diabetic macular edema. This post hoc analysis is based on treatment agnostic data from the phase 3 YOSEMITE and RHINE trials.

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Feb 18 / Roche and Genentech
Retinal Fluid and Thickness Fluctuations in Pagoda Trial of PDS in Patients With DME
This presentation describes results from a post hoc analysis investigating retinal fluid and thickness fluctuations and the impact of these features on vision outcomes in patients with DME in the phase 3 Pagoda trial. In patients with DME, continuous delivery with PDS controlled retinal fluctuations and maintained vision over 48 weeks, comparable to IVT.

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Feb 16 / Roche and Genentech
Implementation of Optimized Surgical Steps for the PDS and the Incidence of Endophthalmitis and Associated Patient Outcomes
This presentation decribes results from a retrospective analysis which examined the impact of surgical improvements on endophthalmitis incidence and patient outcomes over time in patients receiving the Port Delivery Platform with ranibizumab (PDS) in the PDS clinical development program from 2016 to 2024. A trend for improvement in endophthalmitis incidence and patient outcomes was observed after June 2020. Key updates, increased awareness, better monitoring and management in the PDS clinical trial program have all contributed to this positive trend.
09:04 PM
Duration 5mins United States
Treatment Response and Safety of Faricimab▼ in Underrepresented Patients With DME: Year 1 Results From ELEVATUM in the US
Scott A, Amador M, Brown J, Cunningham M, Coney J, Emanuelli A, Huddleston S, Milunovich S, Yang M, Lu XY, Gonzalez L

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09:09 PM
Duration 5mins United States
Four-Year Outcomes of Faricimab▼ in DME: Safety and Efficacy Results From The RHONE-X Long-Term Extension Trial
Khanani A, Abreu F, Gibson K, Kotak A, Lai TYY, Pearce I, Schlottmann P, Sim D, Tang Y, Kotecha A

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09:14 PM
Duration 5mins United States
Greater reduction in hard exudates with faricimab▼ vs aflibercept in patients with DME: biomarker results from the phase 3 YOSEMITE/RHINE trials
Elman M, Pollreisz A, Dinah C, Goldberg R, Ip M, Rahimy E, Vujosevic S, Amador M, Gibson K, Maunz A, O'Leary O, Uschner D

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01:50 PM
Duration 5mins United States
Impact of Early Intraretinal Fluid Reduction on One-Year Outcomes in Diabetic Macular Edema
Chan C, Sadda S, Lim J, Wang Y, Hibar D, Maunz A, Lu H, Albrecht T, Amador M, Gibson K, Litts K

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12:25 PM
Duration 5mins United States
Global Real-World Clinical and Anatomical Outcomes With Faricimab▼ in Treatment-Naïve Patients With nAMD or DME From a Multi-Country Prospective Non-Interventional Study: The VOYAGER Study
Schmitz-Valckenberg S, Bailey C, Chaikitmongkol V, Chaudhary V, Chi G, Downey A, Finger R, Gallego-Pinazo R, Koh A, Ishida S, Lövestam-Adrian M, Parravano M, Pinto JL, Sheth V, Shi B, Souied E, Uschner D, Guymer R

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12:30 PM
Duration 5mins United States
Treatment Patterns, Visual Outcomes, and Safety in Eyes With nAMD and DME Treated With Faricimab▼ in the UK: 1-Year Results From the FARWIDE Study
Sivaprasad S, Pearce I, Talks J, Salvo G, Patel P, Silva S, Gale R, McKibbin M, Varma D, Peto T, Reynolds R, Bailey C, Downey L, Kiire C, Chi G, Dodds M, James N, Downey A, Dayal P

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12:35 PM
Duration 5mins United States
Real-World Clinical Outcomes Update in Patients With Neovascular Age-Related Macular Degeneration (nAMD) and Diabetic Macular Edema (DME) Treated With Faricimab▼ in the US: The FARETINA Study
Borkar D, Zwick E, Bonine N, Leng T, Ko S, Shaia J, Ali F, Singh R

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02:50 PM
Duration 10mins United States
Clinical Impact of Continuous Drug Delivery With the PDS in Patients With nAMD
Arevalo JF, Chakravarthy U, Rachitskaya A, Holekamp N, Blotner S, Garcia Armendariz B, Heinrich D

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03:20 PM
Duration 10mins United States
Comparative Efficacy of Faricimab▼ for the Treatment of Diabetic Macular Edema: A Systematic Literature Review and Network Meta-Analysis
Wells J, Lupidi M, Keane P, Holekamp N, Leng T, Siedlecki J, Mar F, Gibson K, Margaron P, Paulo T, Buehrer C, Tabano D

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03:40 PM
Duration 10mins United States
Baseline and Early Treatment Response Variables Associated With Faricimab▼ Durability in Treatment-nave nAMD: TENAYA/LUCERNE Post Hoc Analyses
Tan C, Gallego-Pinazo R, Koh A, Pitcher J, Dagincourt N, Hill L, Patel S, Margaron P

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03:50 PM
Duration 10mins United States
Faricimab▼ for Polypoidal Choroidal Vasculopathy: Week 16 Results From the Phase 3b/4 SALWEEN Trial
Cheung G, Chen SJ, Iida T, Koh A, Lee WK, Ruamviboonsuk P, Sun X, Yanagi Y, Bai R, Margaron P, Nguyen Duc A, Lai TYY

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09:20 PM
Duration 5mins United States
Interleukin-6 Inhibition With Vamikibart in Patients With Uveitic Macular Edema: DOVETAIL, MEERKAT, and SANDCAT Trials
Holecamp N, Lin P, Steeples L, Elze M, Macgregor L, Stoilov I, Silverman D, Mesquida M, Haskova Z

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02:35 PM
Duration 5mins United States
Implementation of Optimized Surgical Steps for the PDS and the Incidence of Endophthalmitis and Associated Patient Outcomes
Chaudhry N, Campochiaro P, Chang M, Pieramici P, Regillo C, Bobbala A, Gune S, Jaycock P, Kardatzke D, Prager A, Singh N

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04:20 PM
Duration 10mins United States
Retinal Fluid and Thickness Fluctuations in Pagoda Trial of PDS in Patients With DME
Tan G, D Marcus, Awh C, Eter N, Hatz K, Menezes A, Eghoej M, Gordon A, Blotner S, Heinrich D

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