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Home Respiratory Cystic Fibrosis

Cystic Fibrosis

Cystic fibrosis is characterised by widespread dysfunction of exocrine glands which results in a broad array of presenting manifestations and complications.

Secretions from mucous glands in the lungs and gastrointestinal tract are physically altered, becoming unusually thick and viscous. Clinical complications associated with these changes include the development of chronic suppurative bronchitis with destruction of lung tissue, pancreatic insufficiency leading to malabsorption, diabetes mellitus, liver disease and male infertility.

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May 27 / Springer Healthcare
ATS 2021 in-depth report: Cystic Fibrosis
This ATS 2021 in-depth report provides an update on advances in precision medicine in cystic fibrosis.
Respiratory Cystic Fibrosis
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Sep 22 / Springer Healthcare
ERS In-depth Report: Cystic fibrosis
This in-depth report provides an overview of sessions presented at ERS 2020 on the treatment and care of patients with cystic fibrosis.
Respiratory Cystic Fibrosis
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Independent content
Sep 28 / Springer Healthcare
Xenon and helium MRI detect sub-clinical cystic fibrosis lung abnormalities
Laurie Smith tells us the key findings of a study that looked at the relative sensitivities of xenon (129Xe) and helium (1H) MRI for the evaluation of sub-clinical lung disease in children and adults with cystic fibrosis.
Respiratory Cystic Fibrosis ERS-2019

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Sep 8 / Roche and Genentech
Airflow in a small airway vessel of a cystic fibrosis patient
In cystic fibrosis, the thickening of the mucosa and the presence of sputum in the vessel lumen (patches) cause increased resistance and air turbulence during inspiration (widening) and expiration (narrowing). By using a stethoscope, this air turbulence can be heard as a crackling and wheezing sound.
Respiratory Cystic Fibrosis

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Sep 8 / Roche and Genentech
Airflow in a small airway vessel of a healthy person
In a small airway vessel of a healthy person, the laminar airflow passes smoothly alongside the mucosal folds during inspiration (widening) and expiration (narrowing).
Respiratory Cystic Fibrosis

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Aug 21 / Roche and Genentech
Pathophysiology and current treatment options of cystic fibrosis explained to children
This video explains the pathophysiology and current treatment options of cystic fibrosis in plain language. It can be used as a resource by Healthcare Professionals in order to educate patients and their caregivers.
Respiratory Cystic Fibrosis
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This website is intended for healthcare professionals outside the United Kingdom (UK) and Australia. Registration status and prescribing information of medicinal products may differ between countries. Please refer to local product information for any medicinal products mentioned on this website.