Safety of Ocrelizumab in Patients With RRMS With Suboptimal Response to Prior DMTs: Data From the CASTING Study

Patients with RRMS often experience disease activity despite receiving a DMT; however, clinical trial data on the efficacy and safety of OCR in patients with a suboptimal response to prior DMTs are limited. In the Phase IIIb CASTING study (NCT02861014), the efficacy and safety of OCR was evaluated in patients with RRMS who had a suboptimal response to ≥6 months’ treatment with one or two prior DMTs.

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