The tumor microenvironment (TME) and atezolizumab + nab-paclitaxel (A+nP) activity in metastatic triple-negative breast cancer (mTNBC): IMpassion130

This exploratory analysis from IMpassion130 investigated the TNBC tumor microenvironment and its potential association with atezolizumab + nab-paclitaxel (A+nP) efficacy. IMpassion130 is a Phase III study evaluating A+nP vs placebo + nP in metastatic TNBC. This analysis reports molecular pathway characterization and clinical outcomes based on PD-L1 expression, immune phenotypes, and molecular subtypes.

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