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Urinary Bladder Cancer

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Feb 14 / Roche and Genentech
Effectiveness and Safety of First-Line Atezolizumab in Locally Advanced or Metastatic Urothelial Cancer: The IMFLAME Study
The purpose of this analysis is to evaluate the real-word effectiveness and safety of atezolizumab monotherapy as first line treatment in locally advanced or mUC ineligible for platinum-based chemotherapies.

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Sep 15 / Roche and Genentech
Post hoc analysis of outcomes according to prior chemotherapy (CT) response and platinum agent in the international SAUL study of atezolizumab (atezo) for urinary tract carcinoma (UTC)
This poster reports a post hoc analysis of clinical outcomes with atezolizumab in previously treated patients with metastatic urinary tract carcinoma based on response to prior chemotherapy and type of platinum agent, using data from the single-arm prospective SAUL study. Outcomes reported in this subgroup analysis include assesses efficacy, overall survival, overall response rate, and duration of response.

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Sep 12 / Roche and Genentech
Bladder preservation therapy in combination with atezolizumab and radiation therapy for invasive bladder cancer (BPT RT): An open label, single arm, multicenter, phase II
This poster presents an open-label, single-arm multicenter Phase II trial evaluating atezolizumab combined with radiation therapy as bladder preservation therapy in patients with invasive bladder cancer. The poster presents data from an interim analysis on efficacy and safety.

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Independent content
Sep 18 / Springer Healthcare
ESMO 2021 Genitourinary tumour highlights
Delegates seeking the latest in genitourinary cancer research have been treated to a range of key trial findings in the first days of the ESMO Congress 2021.

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Independent content
Sep 18 / Roche and Genentech
What is the optimal perioperative chemotherapy regimen for muscle-invasive bladder cancer?
Srikala Sridhar gives her thoughts on the VESPER V05 trial comparing dose-dense methotrexate, vinblastine, doxorubicin and cisplatin with gemcitabine plus cisplatin as perioperative treatment in people with muscle-invasive bladder cancer.

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Independent content
Sep 18 / Springer Healthcare
Cetrelimab boosts erdafitinib response in advanced urothelial carcinoma
Srikala Sridhar comments on the interim analysis of the NORSE study of first-line erdafitinib plus cetrelimab in cisplatin-ineligible patients with advanced urothelial carcinoma and fibroblast growth factor receptor alterations.

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