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Home Oncology ESMO 2023
Roche and Genentech at

ESMO 2023

October 20 - October 24
Madrid, Spain / Virtual (Hybrid)
esmo.org
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Medical Materials
Agenda
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08:00 AM
Duration 8hrs Madrid, Spain
IMreal Cohort 4: third interim analysis of efficacy and safety in patients (pts) with extensive-stage small cell lung cancer (ES-SCLC) receiving atezolizumab plus carboplatin and etoposide (atezo + CE) as first-line (1L) therapy under real-world conditions
Sanjay Popat, Nicolas Girard, Stefaniya Shoshkova, Gwendoline Kok, José Luis Pérez Gracia
Oncology | Lung Cancer

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Duration 8hrs Madrid, Spain
Atezolizumab and bevacizumab (atezo + bev) ± radiotherapy (RT) vs docetaxel (doc) in checkpoint inhibitor (CPI)–experienced metastatic NSCLC (mNSCLC): results from the Phase Ib/II MORPHEUS-Lung study
Ghiringhelli, Felip E, Zer, Greillier, Greystoke A, Lim, Al-Sakaff N, Helms HJ, Pintoffl J, Gan X, Prizant H, Cho
Oncology | Lung Cancer

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Duration 8hrs Madrid, Spain
Characteristics of patients (pts) with previously treated, oestrogen receptor-positive, HER2-negative advanced breast cancer (ER+, HER2– aBC) who had rapid progression (RP) in acelERA BC
Martín M, Hilz S, Collier A, Chibly A, Sohn J, Bardia A, Lim E, Chavez-MacGregor M, Martinalbo J, Pérez-Moreno PD, Moore HM
Oncology | Breast Cancer

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Duration 1hr Madrid, Spain
WAYFIND-R: A global, real-world database of patients (pts) with a solid tumour profiled with next-generation sequencing (NGS).
Jean-Yves Blay, Allan Hackshaw, Christophe Le Tourneau, Jan Geissler, Ana Ferro, Erika Schirghuber, Olga Skatkova, Rodrigo Dienstmann
Oncology | Solid Tumours

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Duration 8hrs Madrid, Spain
Quality of life (QoL) and toxicity in patients (pts) with hormone receptor-positive, HER2-negative early breast cancer (HR+, HER2– eBC) treated with adjuvant (adj) endocrine therapy (ET) in the CANcer TOxicities (CANTO) study
Bertaut A, Crnjevic TB, Martin A-L, Gaudin C, Chen L
Oncology | Breast Cancer

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Duration 8hrs Madrid, Spain
Alectinib for treatment-naïve advanced ALK+ NSCLC selected via blood-based NGS: updated analyses of outcomes, circulating tumour (ct)DNA and biomarker subgroups from BFAST Cohort A
Gadgeel S, Mok T, Peters S, Nadal E, Han J-H, Alatorre-Alexander J, Leighl N, Sriuranpong V, Perol M, de Castro Junior G, de Marinis F, Tan DSW, Shagan SM, Assaf ZJ, Maclennan M, Ochi Lohmann T, Slade M, Mathisen MS, Prasad V, Dziadziuszko R
Oncology | Lung Cancer

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Duration 8hrs Madrid, Spain
Real-world prognostic value of RET fusions in advanced non-small cell lung cancer (aNSCLC)
Gadgeel S, Zhang Q, Lin H, Fajardo O, Trinh H, Arndorfer S, Kong S, Rahman A, Li S, Archer V, Gainor J
Oncology | Lung Cancer

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Duration 8mins Madrid, Spain
Interim analysis (IA) of the giredestrant (G) + ipatasertib (IPAT) arm in MORPHEUS Breast Cancer (BC): A Phase I/II study of G treatment (tx) combinations in patients (pts) with oestrogen receptor-positive (ER+), HER2-negative, locally advanced/metastatic BC (LA/mBC)
Jung KH, Luen S, Oliveira M, Sohn JH, Im SA, Wander S, Hurvitz S, Sonnenblick A, Breton V, Collier A, Deb S, Ngo H, Schwab R, Shemesh C, Zhu J, Hernando C
Oncology | Breast Cancer

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Duration 1hr Madrid, Spain
Performance Assessment of a Comprehensive Genomic Profiling (CGP) NGS Kit Across Multiple Study Laboratories
Choi J, Fellowes A, Pikarsky E, Teixeira M, Vogl I, Ahmed A, Bi K, Kirkconnell K, Yin C, Shin M, Shrestha N, Blau J, Yin C, Li S, Li Y, Kumar G, Trabucco S, Wen W, Javey M, Zhi L
Oncology | Pan-tumour

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09:35 AM
Duration 10mins Hall 3 (Salamanca Auditorium)
Primary analysis of efficacy and safety in the CUPISCO trial: A randomised, global study of targeted therapy or cancer immunotherapy guided by comprehensive genomic profiling (CGP) vs platinum-based chemotherapy (CTX) in newly diagnosed, unfavourable cancer of unknown primary (CUP)
Linda Mileshkin,Tilmann Bochtler, Chantal Pauli, Gonzalo Durán-Pacheco, Cagatay Arslan, Frédéric Bigot, Nasséra Chalabi, Natalie Cook, Antoine Italiano, Ferran Losa, Juliana Janoski de Menezes,Chantal Michaud, Mustafa Özgüroğlu, Roberto A. Pazo-Cid, Jeffrey S. Ross, Kai-Keen Shiu, Michael Stahl, Marlene Thomas, Holger Moch, Alwin Krämer
Oncology | Carcinoma of Unknown Primary

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02:25 PM
Duration 10mins Hall 9 (Santander Auditorium)
Atezolizumab and tumour microenvironment in early triple-negative breast cancer (eTNBC): Exploratory biomarker analysis from IMpassion031
N. Harbeck, E. Duan, K. DuPree, C-W. Chang, C.H. Barrios, H. Zhang, S. Saji, K.H. Jung, M.L. Telli, M. Liste-Hermoso, S.Y. Chui, M. Dieterich, E. Mittendorf, L. Molinero
Oncology | Breast Cancer

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03:54 PM
Duration 12mins Hall 6 (Madrid Auditorium)
ALINA: efficacy and safety of adjuvant alectinib versus chemotherapy in patients with early-stage ALK+ non-small cell lung cancer (NSCLC)
Prof Benjamin J. Solomon, Prof Jin Seok Ahn, Prof Rafal Dziadziuszko, Prof Fabrice Barlesi Dr Makoto Nishio, Prof Dae Ho Lee, Prof Jong-Seok Lee, Prof Wenzhao Zhong, Dr Hidehito Horinouchi, Prof Weimin Mao, Dr Maximilian Hochmair, Dr Filippo de Marinis, Dr Maria Rita Migliorino, Prof Igor Bondarenko, Dr Tania Ochi Lohmann, Ms Tingting Xu, Mr Andres Cardona, Dr Walter Bordogna, Dr Thorsten Ruf, Prof Yi-Long Wu
Oncology | Lung Cancer

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09:35 AM
Duration 5mins Sevilla Auditorium - Hall 9
A phase II study investigating the safety and efficacy of neoadjuvant atezolizumab in non-urothelial, muscle invasive bladder cancer (ABACUS-2)
Bernadett Szabados, Esther Nogueron Martinez, Francisco José Álvarez Márquez, Daniel Castellano Gauna, Alejo Rodríguez-Vida Rodríguez, Carmen Garcías de España, Syed A Hussain, Carlos Álvarez Fernández, Mark Linch, Teresa Bonfill, Marine Gross-Goupil, John Kelly, Rob Jones, Simon Crabb, Luis Beltran, Rachel Garonce-Hediger, Nikolas Jan Rakebrandt, Ramona Georgescu, Charlotte Ackerman, Thomas Powles
Oncology | Urogenital Cancer

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12:00 PM
Duration 5mins Madrid, Spain
Redefining Lung Cancer Together: A New Era For Patients
Dr Stephen Liu, Dr Lara Pijuan, Prof. Martin Reck, Dr Nasser Altorki, Alba Silverio Pons
Oncology | Lung Cancer

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08:00 AM
Duration 8hrs Madrid, Spain
A global, multicentre, open-label, randomised phase II trial of tobemstomig (tobe) with or without tiragolumab (tira) vs atezolizumab (atezo) in patients (pts) with untreated metastatic urothelial cancer (mUC) ineligible for platinum-based chemotherapy (chemo)
Gupta S, Alhalabi O, Bamias A, Bellmunt J, Castellano D, Bedke J, Friedlander T, Garmezy B, Grivas P, Huddart R, Necchi A, Powles T, Puente J, Rosa D, Wang F, Lambertini C, Andreev-Drakhlin A, Fassò M, Loriot Y.
Oncology | Urogenital Cancer

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Duration 8hrs Madrid, Spain
ESMO 2023 IMscin001 Part 2 updated results: Efficacy, safety, immunogenicity and patient-reported outcomes (PROs) from the randomised Phase III study of atezolizumab (atezo) subcutaneous (SC) vs intravenous (IV) in patients with locally advanced or metastatic non-small cell lung cancer (NSCLC)
Burotto M, Zvirbule Z, Busayamas C, Alvarez R, Herraez-Baranda L, Shearer-Kang E, Liu XY, Tosti N, Castro Y, Zanghi J, Felip E (Order TBC)
Oncology | Lung Cancer

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Duration 8hrs Madrid, Spain
Phase I study of IL-8 inhibitor AMY109 plus atezolizumab (atezo) in patients (pts) with advanced solid tumours
Kuboki Y, Kitano S, Ikeda M, Koyama T, Mizugaki H, Narikiyo T, Yamaguchi Y, Ishida T, Takubo R, Ogami C, Sekiya M, Nakagawa Y, Yamamoto N
Oncology | Solid Tumours

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Duration 8hrs Madrid, Spain
Updated efficacy and safety data of entrectinib▼ in patients with locally advanced/metastatic NTRK fusion-positive (fp) solid tumours
Lu S, de Braud F, Fan Y, Hu X, Ohe Y, Yu Y, Ahn M-J, Cassier P, Lin JJ, Paz-Ares L, Xue C, Bordogna W, Patel S, Zeuner H, Dong X
Oncology | Lung Cancer

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08:10 AM
Duration 5mins Hall 3 (Salamanca Auditorium)
First results from the ENGOT-GYN2/GOG-3051/BOUQUET phase 2 biomarker-directed platform study: cobimetinib (cobi) or atezolizumab (atezo) + bevacizumab (bev) for persistent/recurrent rare epithelial ovarian cancer (eOC)
Ray-Coquard I, Pignata S, Lee J-L, Coleman R, Rothfuss E, Brown J, Kim J-W, Selle F, Lorusso D, Bermejo Perez MJ, Pautier P, Gourley C, Ayhan A, Richardson G, Yauch L, Dieterich M, Krishnan V, Calas-Zeroug O, Harter P, Gershenson D
Oncology | Ovarian Cancer

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01:50 PM
Duration 5mins Hall 9 (Sevilla Auditorium)
IMpower010: exploratory analysis of disease-free survival (DFS) by TGF cancer-associated fibroblast (CAF) gene signature expression in patients (pts) with resected NSCLC treated with atezolizumab (atezo) or best supportive care (BSC)
Nasser Altorki, Martin Reck, Heather Wakelee, Enriqueta Felip, Eric Vallieres, Rüdiger Liersch, Satoshi Oizumi, Hiroshi Tanaka, Silvia Novello, Steven McCune, Haocheng Li, Luciana Molinero, Sören Müller, Elizabeth Bennett, Barbara J. Gitlitz, Virginia McNally, Marcus Ballinger, Barzin Nabet, Minu K. Srivastava, Caicun Zhou
Oncology | Lung Cancer

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This website is intended for healthcare professionals outside the United Kingdom (UK) and Australia. Registration status and prescribing information of medicinal products may differ between countries. Please refer to local product information for any medicinal products mentioned on this website.