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Intrathecal drug delivery of antisense oligonucleotides in Huntington’s disease: Experience of Ionis/Roche RG6042 development programme and best practice considerations for real-world use

RG6042 is an intrathecally-administered antisense oligonucleotide which targets huntingtin mRNA in patients with HD. This poster presents the experience to date with intrathecal drug delivery across two clinical studies of RG6042, including suggested best practice and real world considerations

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