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heredERA Breast Cancer: Phase III study of first-line, fixed-dose combination of pertuzumab and trastuzumab for subcutaneous injection ± giredestrant (GDC-9545) for estrogen receptor+, HER2+ advanced breast cancer

This poster presents an overview of the heredERA Breast Cancer study, a phase III, randomised, open-label study evaluating the efficacy and safety of giredestrant in combination with PH FDC SC versus PH FDC SC after induction therapy with PH FDC SC plus taxane in patients with previously untreated ER-positive, HER2-positive locally advanced or metastatic breast cancer (NCT05296798). Study design, endpoints, enrolment, participating counties, and key eligibility criteria are reported.

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