Gazyva and Use of In-Line Filter
This response corresponds to your request for information on use of in-line filters with Gazyva® (obinutuzumab).
Last updated August 10, 2023
Adminstration requirement
There is no requirement to use an in-line filter during Gazyva adminstration.[1] Use of an in-line filter is optional.
Use of in-line filter in in-use stability studies
In-line filter size
In an in-use stability study, Gazyva IV solution diluted in 0.9% sodium chloride was compatible with use of a 0.22µm in-line filter made from polyethersulfon (PES).[2]
Material compatibilities of in-line filter
Gazyva IV solution diluted in 0.9% sodium chloride to concentrations between 0.4 mg/mL to 20.0 mg/mL was compatible with the following product contact surfaces
- PES
- Polycarbonate (PC) 3-way stockcock infusion aid, and
- Polyethereurethane (PEU) cathether.[1]
References
- Roche Internal Regulatory Document (Accessed on 30 Jun 2023).
- Roche Internal Technical Report (Accessed on 24 Jul 2023).
Medinfo
Need to contact Roche?
Request Product Information
Request Product Information
Ask us a question and request information about Roche products or services.
Report a potential side effect
Report a potential side effect
If you have experienced potential side effects with a Roche product you can report it here.
Report a potential product defect
Report a potential product defect
If you suspect a potential defect or a Roche product has not met your expectations you can report it here.
Request temperature stability assessment
Request temperature stability assessment
Request an assessment if your product was stored outside the recommended temperature range.
