While mass spectrometry (mass spec) has historically been a common basic research tool, it has increasingly gained adoption for diagnostic testing in the clinical setting over the last decade. Clinical labs now utilize mass spec in routine to enhance the sensitivity and specificity of diagnostic testing, such as steroid testing in endocrinology or therapeutic drug monitoring.

The technology behind:  

Mass spec is an analytical technique that measures the mass-to-charge ratio (m/z) of molecules, such as e.g. small molecules and drugs, in a sample. 

• Mass spec offers better sensitivity and specificity for identifying molecular structure of compounds compared to traditional methods.

• By adopting mass spec automation, lab leaders can help improve patient management in multiple care areas, including endocrinological diseases and  therapeutic drug monitoring

In the following tabs you will find publications and congress material discussing the latest developments in Mass Spectrometry. In particular, data on therapeutic drug monitoring (TDM), vitamin D and steroids among others are presented. Please note that the discussed results derive from medical educational events, studies and publications with Roche involvement. In the future scientific content on drugs of abuse testing (DAT) and other analytes will be included.