Patients with a tumor thrombus in the main trunk and/or contralateral portal vein (PVTT stage Vp4) are often excluded from pivotal HCC trials due to their poor prognosis. The IMbrave150 study investigated atezolizumab + bevacizumab vs sorafenib in patients with unresectable HCC who have not received prior systemic therapy. This presentation reports exploratory efficacy and safety results from IMbrave150 in patients with or without PVTT stage Vp4.
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