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Roche and Genentech at

2024 ASCO Annual Meeting

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Coming soon
02:00 PM
Duration 3hrs Chicago USA
Ipatasertib in patients with AKT1/2/3 mutation-positive (AKTmut) tumors: TAPISTRY study
Thomas D, Daniele G, Kim J-E, Gadgeel S, Ahn E, Paz-Ares L, Prenen H, Chen D, Fang J, Wilson TR, Simmons B, Barlesi F

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Duration 3hrs Chicago USA
Genetic drivers of severe skin toxicity with immune checkpoint inhibitors (ICIs) in Asian patients
Yoshimine K, Goto H, Yamada K, Fukuyama T, Oda T, Iwakami R, Takahashi T, Kaul M, Chandler SG, Mohindra R, Madjar K

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Duration 3hrs Chicago USA
MyTACTIC: activity of targeted therapy in patients (pts) with advanced solid tumors harboring specific biomarkers
Schwartzberg LS, Spigel DR, Vanderwalde A, Zuniga R, Hong J, Szado T, Yoo B, Passler L, Wong W, Darbonne WC, Daniel D

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Duration 3hrs Chicago USA
Inequities in timely treatment initiation for patients with acute myeloid leukemia treated in a predominantly community setting in the United States
Ma E, Eisfeld A-K, Odenike O, Patel A, Wang R, Yellow-Duke A, Montez M, Xu Y, Miu K, Hantel A

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06:30 PM
Duration 3hrs Chicago USA
Atezolizumab, cobimetinib, and vemurafenib in patients with BRAFV600 mutation-positive melanoma with central nervous system metastases: Final results and exploratory biomarker analysis from the phase 2 TRICOTEL study
Dummer R, Levesque M, Bellini E, Chen M, Hu Y, Wong T, Stassen K, Duhard P, Yan Y, Tawbi H

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08:00 PM
Duration 180mins S100bc / Live Stream
Glofitamab monotherapy in patients with heavily pretreated relapsed/refractory (R/R) mantle cell lymphoma (MCL): updated analysis from a Phase I/II study
Phillips T, Carlo-Stella C, Morschhauser F, Bachy E, Crump M, Trneny M, Bartlett NL, Zaucha J, Wrobel T, Offner F, Filezac de L'Etang A, Relf J, Carlile DJ, Byrne B, Mulvihill E, Lundberg L, Dickinson M

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Duration 180mins Chicago, USA
First-line inavolisib/placebo + palbociclib + fulvestrant (Inavo/Pbo+Palbo+Fulv) in patients (pts) with PIK3CA-mutated, hormone receptor-positive, HER2 negative locally advanced/metastatic breast cancer who relapsed during/within 12 months (mo) of adjuvant endocrine therapy completion: INAVO120 Phase III randomized trial additional analyses
Juric D, Kalinsky K, Turner N, Jhaveri K, Schmid P, Loi S, Saura C, Im SA, Sunpaweravong P, Li H, Musolino A, Zhang Q, Nowecki Z, Leung R, Thanopoulou E, Shankar N, Lei G, Devine J, Stout T, Loibl S

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01:00 PM
Duration 180mins S100bc | Live Stream
Efficacy and safety of entrectinib▼ in children with extracranial solid or primary central nervous system (CNS) tumors harboring NTRK or ROS1 fusions
Desai A, Robinson G, Wu Y, Wang H, Basu E, Bagchi A, Casanova M, van Tilburg C, Campbell-Hewson Q, Armstrong AE, Andre N, Devlin CE, Wulff J, Cardenas A, Meneses-Lorente G, Hutchinson KE, Lian Q, Ryklansky C, Fox E, Gajjar A

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02:00 PM
Duration 3hrs Chicago USA
Association of machine learning (ML) derived histological features with transcriptomics based molecular subtypes in advanced renal cell carcinoma (RCC)
Niha Beig, Shima Nofallah, David McDermott, Robert Motzer, Thomas Powles, Brian Rini, Hartmut Koeppen, Romain Banchereau, Miles Markey, Isaac Finberg2, Geetika Singh2, Lauren Brunner2, Robert Egger2, Chintan Parmer, Jake Conway, Stephanie Hennek, Dan Ruderman, Samuel Vilchez, Mahrukh Huseni, Jennifer Giltnane

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Duration 3hrs Chicago USA
INAVO121: Phase III study of inavolisib (INAVO) + fulvestrant (FUL) vs. alpelisib (ALP) + FUL in patients (pts) with hormone receptor-positive, HER2-negative (HR+, HER2-), PIK3CA-mutated (mut) locally advanced or metastatic breast cancer (LA/mBC)
Juric D, Kalinsky K, Im SA, Ciruelos E, Bianchini G, Barrios C, Jacot W, Schmid P, Loi S, Rugo H, Craine V, Huchinson K, Flechais A, Thanopoulou E, Harbeck N

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Duration 3hrs Chicago USA
INAVO122: A Phase III study of maintenance inavolisib or placebo + pertuzumab + trastuzumab following induction with pertuzumab + trastuzumab + a taxane in patients (pts) with PIK3CA-mutated, HER2-positive advanced breast cancer (HER2+ aBC)
Swain S, Barrios C, Basho R, Curigliano G, Harbeck N, Huang CS, Karmo M, Loi S, Tolaney S,Turner N, Collier A, Henschel V, Swat A, Warburton S, Amair-Pinedo F, Corts J

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Duration 3hrs Chicago USA
pionERA Breast Cancer is a Phase III study of first-line giredestrant vs. fulvestrant, both combined with a cyclin-dependent kinase 4/6 inhibitor, in patients with estrogen-receptor positive, HER2-negative locally advanced/metastatic breast cancer with resistance to prior adjuvant endocrine therapy
Kalinsky K, Jeselsohn R, Bellet M, Fasching P, Gomez-Abuin G, Jung KH, Lavalle S, Valverde VL, Lu YS, Schwab R, Turner N, Xu T, Zambelli A, Andre F

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Duration 3hrs Chicago USA
Interim analysis (IA) of the giredestrant (G) + everolimus (EVERO) arm in MORPHEUS Breast Cancer (BC): A Phase I/II study of G treatment (tx) combinations in patients (pts) with estrogen receptor-positive (ER+), HER2-negative, locally advanced/metastatic BC (LA/mBC)
Wander S, Stemmer S, Rugo H, Im S, Lau P, Paluch-Shimon S, Cahuzac C, Collier A, Shah M, Ngo H, Schwab R, Zhu J, Oliveria M

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03:00 PM
Duration 3hrs Chicago USA
Real-world treatment patterns, healthcare resource utilization and costs of care among newly diagnosed patients with HR+/HER2- metastatic breast cancer
Abbass I, Ng C, Dillon A, Cheng A, Chen L, Du Toit Y, Basho R

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Duration 3hrs Chicago USA
Economic Impact of Longer Treatment Duration in First-Line for HR+/HER2- Metastatic Breast Cancer: A Retrospective Analysis
Abbass I, Ng C, Dillon A, Cheng A, Du Toit Y, Basho R

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05:00 PM
Duration 90mins S406 | On Demand
HLA associations with immunotherapy related endocrine toxicity
Quandt Z, Thorball J, Middha P, Johnson DB, Bejan CA, Yao L, Xu Y, Hodel F, Stravodimou A, Shearer-Kang E, Liu G, Aldrich M, Schoenfield A, Ziv E, Phillips EJ, Fellay J, Bergmann E, Chandler S, Balko J, Shah A

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01:00 PM
Duration 180mins Arie Crown Theater | Live Stream
Health-related quality of life (HRQoL) results for adjuvant alectinib vs chemotherapy in patients with resected ALK+ non-small cell lung cancer (NSCLC): data from ALINA
Nishio M, Wu Y-L, Barlesi F, Ahn JS, Lee DH, Lee J-S, Zhong W, Horinouch H, Hockmair M, Tanaka H, Glogowski M, Rittmeyer A, Filder M, Wrona A, Mamolo C, Cardona A, Ruf F, Smoljanovic V, Solomon BJ

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Duration 180mins Arie Crown Theatre
BEAT-SC: A randomized Phase III study of bevacizumab or placebo in combination with atezolizumab, chemotherapy and etoposide in patients with extensive-stage small cell lung cancer (ES-SCLC)
Yuichiro Ohe, Makoto Nishio , Baohui Han, Satoshi Watanabe, Xiubao Ren, Shuji Murakami, Nong Yang, Isamu Okamoto, Gaofeng Li, Nobuyuki Katakami, Xianling Liu, Naoyuki Nogami, Yuki Nakagawa, Morihiko Hayashi, Toshihiro Nanki, Chunyu Qian, Nobuyuki Yamamoto

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Duration 90mins Chicago, USA
Circulating KIM-1 biomarker analysis in IMmotion010, a randomized Phase 3 study of adjuvant atezolizumab (atezo) vs placebo (pbo) in patients with renal cell carcinoma (RCC) at increased risk of recurrence after resection
Laurence Albiges, Axel Bex, Cristina Suarez, Robert Uzzo, Xiaobin Tang, Zoe June Assaf, Sarita Dubey, Erik Goluboff, Corey Carter, Romain Banchereau, Mahrukh Huseni, Sumanta Pal, Brian Rini

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02:00 PM
Duration 3hrs Chicago USA
Glofitamab monotherapy retreatment in patients with heavily pre-treated relapsed or refractory (R/R) non-Hodgkin lymphoma (NHL): results from a Phase I/II study
Bartlett NL, Dickinson M, Hutchings M, Carlo-Stella C, Wu S-J, Leppa S, Trneny M, Corradini P, Offner F, Mulvihill E, Bottos A, Tchaleu FB, Baumlin P, Relf J, Lundberg L, Bachy E

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Duration 3hrs Chicago USA
Real-world patient outcomes in biomarker-selected early non-small cell lung cancer patients
Fawzi Abu Rous, Jesse Sussell, Celina Ngiam Kochounian, Qing Zhang, Thomas Majda, Danny Sheinson, Sarika Ogale, Ilze Bara, Katja Schulze, Shirish Gadgeel

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Duration 3hrs Chicago USA
Genomic profiling in a subgroup analysis of patients (pts) with diffuse large B-cell lymphoma (DLBCL) and extranodal (EN) sites of involvement in the Phase III Pola-R-CHP vs R-CHOP (POLARIX) study
Lue JK, Morschhauser F, Tilly H, Lenz G, Jardin F, Herrera AF, Sharman JP, Flowers CR, Friedberg JW, Trněný M, Herbaux C, Yan M, Jiang Y, Hirata JH, Batlevi CL, Sugidono M, Sahin D, Leung W, Harris W, Salles G, Sehn LH

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Duration 3hrs Chicago USA
Mosunetuzumab with polatuzumab vedotin: subgroup analyses in patients (pts) with primary refractory or early relapsed large B-cell lymphoma (LBCL)
Assouline S, Budde LE, Chavez JC, Diefenbach C, Dorritie K, Ghosh N, Olszewski AJ, Lossos IS, Mehta A, Modi D, Naik S, Smith SD, Makadia S, Pham S, Wu H, Batlevi CL, To I, Wei MC, Kamdar M

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06:30 PM
Duration 3hrs Chicago USA
Krascendo-170 Lung: A phase Ib/II study of divarasib + pembrolizumab ± platinum-based chemotherapy and pemetrexed in untreated KRAS G12C+ advanced non-small cell lung cancer (NSCLC)
Skoulidis F, Cuppens K, Sacher A, Velcheti V, Lee D-H, Lin MT, Fernando TM, Li S, Bradley D, Zarak Crnkovic M, Mathisen M

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Duration 3hrs Chicago USA
ALK testing patterns in early non-small cell lung cancer: A real-world evidence study
Ticeana Leal, Jesse Sussell, Celina Ngiam Kochounian, Qing Zhang, Thomas Majda, Danny Sheinson, Sarika Ogale, Ilze Bara, Katja Schulze, Jason Porter

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Duration 3hrs Chicago USA
Budget Impact Model of LungFlag™, a Predictive Risk Model for Lung Cancer Screening
Michael K. Gould, Eran Choman, Nicolò Olghi, Milan Obradovic, Sarika Ogale, Carolina Heuser Sanmartin

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Duration 3hrs Chicago USA
IMpower010: Disease-Free Survival Final Analysis and Second Overall Survival Interim Analysis Results After ≥5 years of Follow-up of a Phase III Study of Adjuvant Atezolizumab vs Best Supportive Care in Resected Stage IB-IIIA Non-Small Cell Lung Cancer
Heather A. Wakelee, Nasser Altorki, Caicun Zhou, Tibor Csőszi, Ihor O. Vynnychenko, Oleksandr Goloborodko, Achim Rittmeyer, Martin Reck, Alex Martinez-Marti, Hirotsugu Kenmotsu, Yuh-Min Chen, Antonio Chella, Shunichi Sugawara, Chenqi Fu, Marcus Ballinger, Yu Deng, Minu K. Srivastava, Elizabeth Bennett, Barbara J. Gitlitz, Enriqueta Felip

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Duration 3hrs Chicago USA
J-TAIL-2: A prospective observational study of atezolizumab (atezo) combination therapy in patients with non-small cell lung cancer (NSCLC) in Japan
Yasutaka Watanabe, Makoto Nishio, Kadoaki Ohashi, Atsushi Osoegawa, Eiki Kikuchi, Hideharu Kimura, Yasushi Goto, Junichi Shimizu, Eisaku Miyauchi, Hiroshige Yoshioka, Ichiro Yoshino, Toshihiro Misumi, Masafumi Yamaguchi, Kozo Yoshimori, Masahiro Seike, Hironori Yoshida, Kazumi Nishino, Asako Miwa, Misa Tanaka, Akihiko Gemma

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Duration 3hrs Chicago USA
J-TAIL-2: A prospective, observational study of atezolizumab (atezo) combined with carboplatin and etoposide (CE) in patients (pts) with extensive-stage small cell lung cancer (ES-SCLC) in Japan
Ryota Saito, Masato Nishio, Kadoaki Ohashi, Atsushi Osoegawa, Eiki Kikuchi, Hideharu Kimura, Yasushi Goto, Junichi Shimizu, Eisaku Miyauchi,Hiroshige Yoshioka, Ichiro Yoshino, Toshihiro Misumi, Takashi Kijima, Kenichi Chikamori, Hisashi Tanaka, Kazunori Tobino, Tatsuro Fukuhara, Hirotaka Kuroki, Misa Tanaka, Akihiko Gemma

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01:00 PM
Duration 90mins S406 | On Demand
Atezolizumab in patients with tumor mutational burden-high (TMB) tumors from the TAPISTRY trial
Dziadziuszko R, Barlesi F, Kim J-E, Gadgeel S, Krzakowski M, Jeong J-H, Daniele G, Chen, D, Hu Y, Wilson T, Simmons B, Thomas D

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