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Home Neuroscience AAN 2024
Roche and Genentech at

AAN 2024

April 13 - April 18
Denver, USA / Virtual (Hybrid)
aan.com
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Medical Materials
Agenda
Coming soon
02:00 PM
Duration 1hr Denver, USA
Teleneurology visits had similar to lower odds of completion of AAN multiple sclerosis quality measures compared to in-person visits
Samantha Stallkamp, Sarita Walvekar, Kelly Brown, Saswat Sahoo, Mengke Du, Elizabeth S. Mearns, Nikki Win, Marisa McGinley
Neuroscience | Multiple Sclerosis

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05:45 PM
Duration 1hr Denver, USA
Variation in the Use of Disease-Modifying Therapies in Persons with Multiple Sclerosis by Age
Caroline K Geiger, Rongrong Wang, Carmen Ng
Neuroscience | Multiple Sclerosis

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Duration 1hr Denver, USA
Protocol for a Delphi Consensus Panel on Assessing Clinically Meaningful Treatment Outcomes in Adults Living with Spinal Muscular Atrophy (SMA)
K Sully, CA Chiriboga, T Duong, Y Erbas, J Glascock, N Gusset, R Muni-Lofra, C O’Connell, JF Vázquez-Costa, MC Walter, CJ Guittari, J Cochrane, LD Townson, A Marciniak, D Riley, J Nam
Neuroscience | Spinal Muscular Atrophy

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Duration 1hr Denver, USA
A retrospective, non-interventional cohort study to compare adults with SMA receiving risdiplam▼ with untreated patients: Study design
CJ Guittari, M Batech, A Carmona, SY Lee, A Poll, A Simpson, S Edwards, CS Sutherland, C Marini-Bettolo, MC Walter, M Jagut, J Haberlová, V Hodgkinson, E Yiu, LB Murphy, TREAT-NMD Global Data systems Oversight Committee (TGDOC), TREAT-NMD Global Registry Network for SMA, T Roe, H Gordish-Dressman
Neuroscience | Spinal Muscular Atrophy

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Duration 60mins Denver, USA
Moving upstream: The role of interleukin-6 in MOGAD and autoimmune encephalitis
Ivana Vodopivec
Neuroscience - Inflammatory Disease | Autoimmune Encephalitis - Myelin oligodendrocyte glycoprotein antibody disease

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10:08 PM
Duration 12mins S7: Multiple Sclerosis in: Special Populations and Non-MS CNS Neuroinflammatory Diseases
Pregnancy and Infant Outcomes in Females Receiving Ocrelizumab for the Treatment of Multiple Sclerosis: Analysis of over 3,000 Pregnancies to Date
R Bove, C Pietrasanta, C Oreja-Guevara, K Hellwig, R Dobson, S Vukusic, C-J Lin, D Goncalves Pereira Alves, D Zecevic, G Ferreira, L Craveiro, N Pasquarelli, T McElrath
Neuroscience | Multiple Sclerosis

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05:21 PM
Duration 6mins ES1: Emerging Science 1
Oral Presentation: Primary and secondary results of LUMINESCE, a Phase 3 study of interleukin-6 signaling inhibition by satralizumab▼ in generalized myasthenia gravis
Ali. A. Habib, Chongbo Zhao, Inmaculada Aban, Marcondes Cavalcante França Jr., Jorge Gustavo José, Gerd Meyer zu Hörste, Elżbieta Klimiec-Moskal, Michael T. Pulley, Darío Tavolini, Kathleen Blondeau, Petranka Krumova, Siân Lennon-Chrimes, Gian-Andrea Thanei, Ivana Vodopivec, Gil I. Wolfe, Hiroyuki Murai
Neuroscience | Myasthenia gravis

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06:10 PM
Duration 30mins Denver, USA
Poster: Primary and secondary results of LUMINESCE, a Phase 3 study of interleukin-6 signaling inhibition by satralizumab▼ in generalized myasthenia gravis
Ali. A. Habib, Chongbo Zhao, Inmaculada Aban, Marcondes Cavalcante França Jr., Jorge Gustavo José, Gerd Meyer zu Hörste, Elżbieta Klimiec-Moskal, Michael T. Pulley, Darío Tavolini, Kathleen Blondeau, Petranka Krumova, Siân Lennon-Chrimes, Gian-Andrea Thanei, Ivana Vodopivec, Gil I. Wolfe, Hiroyuki Murai
Neuroscience | Myasthenia gravis

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11:30 PM
Duration 29mins Denver, USA
Clinical Applications of Digital Biomarkers in Multiple Sclerosis: A Systematic Literature Review
Bryan Cobb, Richard J. Karpowicz, Jr., Chris Cousin, Nikki Win, Tina Boggiano, David E. Jones, Licinio Craveiro, Jessica Priest, Ami Mac, Edmond Teng, E. Ray Dorsey, Marwan N. Sabbagh, Mark Gudesblatt, Bart M. Demaerschalk, David W. Dodick
Neuroscience | Multiple Sclerosis

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Duration 29mins Denver, USA
Prediction of Long-Term Adherence to Smartphone Sensor-Based Tests (Floodlight)
MP McGinley, G Pointeau, M Zanon, L Leocani, G Comi, F Lipsmeier, L Craveiro, H Butzkueven
Neuroscience | Multiple Sclerosis

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03:15 PM
Duration 15mins Clinical Trials Plenary Session
One-Year Analysis of Efficacy and Safety Data From Black/African American and Hispanic/Latino People With Relapsing Multiple Sclerosis Receiving Ocrelizumab Treatment in the CHIMES Trial
Lilyana Amezcua, Nancy L Monson, Mitzi J Williams, Timothy Vartanian, Anthony T Reder, Krupa Pandey, Kottil Rammohan, Barry Hendin, Gregory F Wu, Rikisha Parekh, Jinglan Pei, Ibraheem Abioye, Juan Acosta, Evanthia Bernitsas
Neuroscience | Multiple Sclerosis

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Duration 15mins Clinical Trials Plenary Session
Referral Patterns from Primary Care Clinicians to Specialists Among People with Neurological Disorders
Elizabeth S. Mearns, Daniel Sheinson, Kimberly Jinnett, Anisha M. Patel, Abhishek Gaur, Christine J. Macaluso, Jonathan M. Weiss, Nikki Win
Neuroscience | Multiple Sclerosis

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Duration 15mins Clinical Trials Plenary Session
Disease Burden of Neurological Disorders in Underserved Populations Across the US in 2022
Anisha M Patel, Elizabeth S Mearns, Stacey Kowal, Katherine L Rosettie, Nikki Win
Neuroscience | Multiple Sclerosis

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05:45 PM
Duration 1hr Denver, USA
Estimates of Productivity Loss Due to Neurological Diseases in the United States
Julia Fox, Elizabeth Mearns, Thomas Majda, Kate Rosettie, Nikki Win, Stacey Kowal
Neuroscience | Multiple Sclerosis

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02:00 PM
Duration 1hr Denver, USA
The Safety Profile of Fenebrutinib in Patients With Multiple Sclerosis Is Consistent With Those In Previously Studied Autoimmune Indications
Jiwon Oh, Anastasiia Raievska, Malgorzata Sierzega, Joao Cerqueira, Claire S. Riley, Maresa Caunt, John N. Ratchford, Alexandra Goodyear, Konstantina Vanevski, Maria Pia Sormani, Gavin Giovanonni
Neuroscience | Multiple Sclerosis

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Duration 60mins Denver, USA
Ocrelizumab in Patients With Early-Stage RRMS – Results From The Phase IIIb ENSEMBLE Trial and The Matched Real-World NTD MS Registry Cohort
HP Hartung, T Holmøy, J Wuerfel, Y Heer, S Braune, A Bergmann, M Zuercher, S. Guye, T Kuenzel, S Moore, T Vollmer, on behalf of the NTD study group
Neuroscience | Multiple Sclerosis

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05:45 PM
Duration 1hr Denver, USA
A Two-Part, Phase I Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Fenebrutinib (Part A) and the Effect of Fenebrutinib on the QT/QTc Interval in Healthy Participants (Part B)
Yan Xu, Denison Kuruvilla, John N Ratchford, Qi Qi, Lin Pan, Jiajie Yu
Neuroscience | Multiple Sclerosis

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Duration 1hr Denver, USA
Burdens of Neuromyelitis Optica Spectrum Disorder: Real-World Perspectives From Caregivers
Anisha M. Patel, Ashley Martin, Kacper Perkowski, Kathryn Krupsky, Patrick Olsen, Shervin Gholizadeh, Jacinta Behne, Megan K. Behne, Kim Jackson-Matthews, Lisa McDaniel, Cori Woolf, Michael R. Yeaman
Neuroscience | Neuromyelitis Optica

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Duration 60mins Denver, USA
LUMINESCE, a Phase 3 study of satralizumab▼ in generalized myasthenia gravis (gMG): Baseline Characteristics
Ali. A. Habib, Chongbo Zhao, Inmaculada Aban, Marcondes Cavalcante França Jr., Jorge Gustavo José, Gerd Meyer zu Hörste, Elżbieta Klimiec-Moskal, Michael T. Pulley, Darío Tavolini, Petranka Krumova, Siân Lennon-Chrimes, Jillian Smith, Ivana Vodopivec, Gian-Andrea Thanei, Gil I. Wolfe, Hiroyuki Murai
Neuroscience | Myasthenia gravis

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Duration 60mins Denver, USA
Infection in NMOSD: Analyzing the patterns of infection in the SAkura studies, satralizumab▼ post-marketing data, and NMOSD US PharMetrics claims data
Benjamin M. Greenberg, Kazuo Fujihara, Brian Weinshenker, Francesco Patti, Ingo Kleiter, Jeffrey L. Bennett, Jacqueline Palace, Miriam Triyatni, Kathleen Blondeau, Alexander Burdeska, Innocent Ngwa, Gaëlle Klingelschmitt, Takashi Yamamura
Neuroscience | Neuromyelitis Optica

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Duration 60mins Denver, USA
OCARINA I, Phase Ib Study: Dose Selection of Subcutaneous Ocrelizumab in Patients With Multiple Sclerosis
SD Newsome, L Goldstick, B Townsend, D Zecevic, A Augustin, C Figueiredo, S Clinch, C Giacobino, O Bortolami, YA Shen, H Kletzl, R Bermel
Neuroscience | Multiple Sclerosis

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Duration 60mins Denver, USA
Low Disease Activity Over 4 Years of Ocrelizumab Therapy in Treatment-Naive Patients With High-Activity, Early-Stage Relapsing-Remitting Multiple Sclerosis in the ENSEMBLE Study
HP Hartung, R Bermel, B Brochet, WM Carroll, MS Freedman, T Holmøy, R Karabudak, J Killestein, C Nos, F Patti, L Vanopdenbosch, T Kuenzel, K Kadner, I Kulyk, T Berger on behalf of the ENSEMBLE Investigators and Steering Committee
Neuroscience | Multiple Sclerosis

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07:00 PM
Duration 12mins S31: Multiple Sclerosis: Therapeutics and Clinical Decision Making
Subcutaneous Ocrelizumab in Patients with Multiple Sclerosis: Results of the Phase III OCARINA II Study
SD Newsome, E Krzystanek, K Selmaj, L Goldstick, C Figueiredo, B Townsend, C Wolf, D Zecevic, C Giacobino, O Bortolami, YA Shen, H Kletzl, S Clinch, D Centonze
Neuroscience | Multiple Sclerosis

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07:12 PM
Duration 12mins S32: Autoimmune Neurology: NMOSD/MOGAD
Long-term efficacy of satralizumab▼ in patients with AQP4-IgG+ NMOSD: Updated analysis from the open-label SAkuraMoon study
Jacqueline Palace, Anthony Traboulsee, Albert Saiz, Jerome De Seze, Ingo Kleiter, Jeffrey L. Bennett, Daniela Stokmaier, Gaëlle Klingelschmitt, Audrey Yeo Te-ying, Ivana Vodopivec, Takashi Yamamura
Neuroscience | Neuromyelitis Optica

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07:36 PM
Duration 12mins S31: Multiple Sclerosis: Therapeutics and Clinical Decision Making
Cerebrospinal Fluid and MRI Analyses of Fenebrutinib Treatment in Multiple Sclerosis Reveal Brain Penetration and Early Reduction of New Lesion Activity: Results From the Phase II FENopta Study
Amit Bar-Or, Michal Dufek, Hrvoje Budincevic, Jelena Drulovic, Mario Habek, Le H Hua, Martin S Weber, Piia Thomas, Julie Napieralski, David Clayton, Denison Kuruvilla, Qi Qi, Yan Xu, Alexandra Goodyear, Jiwon Oh
Neuroscience | Multiple Sclerosis

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07:48 PM
Duration 12mins S31: Multiple Sclerosis: Therapeutics and Clinical Decision Making
10 Years of Ocrelizumab Treatment in Multiple Sclerosis: Long-Term Efficacy and Safety Clinical Trial Data
SL Hauser, L Kappos, M Filippi, JS Wolinsky, MS Weber, JA Nicholas, C Chognot, HM Schneble, Q Wang, G Giovannoni, X Montalban
Neuroscience | Multiple Sclerosis

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08:00 PM
Duration 12mins S30: Movement Disorders: Clinical Trials in Movement Disorders
Exploratory Analysis of PASADENA Open-label Extension Evaluating the Effect of Prasinezumab on the Progression of Motor Signs and Symptoms
Patrik Brundin
Neuroscience | Parkinson's Disease

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10:30 PM
Duration 12mins S37: Emerging Therapies in Child Neurology
RAINBOWFISH: Primary efficacy and safety data in risdiplam▼-treated infants with presymptomatic spinal muscular atrophy (SMA)
L Servais, MA Farrar, RS Finkel, D Vlodavets, E Zanoteli, M Al-Muhaizea, APQC Araujo, L Nelson, B Jaber, K Gorni, H Kletzl, L Palfreeman, E Gaki, M Rabbia, D Summers, P Fontoura, E Bertini, on behalf of the RAINBOWFISH Study Group
Neuroscience | Spinal Muscular Atrophy

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