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CMSC 2023

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Jun 1 / Roche and Genentech
Long-term Efficacy of Satralizumab▼ in Adults With Aquaporin-4-IgG-seropositive (AQP4-IgG+) Neuromyelitis Optica Spectrum Disorder (NMOSD): Results from SAkuraMoon
This study presents the long-term efficacy of satralizumab▼ in adult patients with AQP4-IgG+ NMOSD who rolled over from the SAkuraSky and SAkuraStar studies into the single-arm, open-label study SAkuraMoon.

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May 31 / Roche and Genentech
Clinical simulation as a novel approach to evaluate digital health solutions: Floodlight MS case study
There is growing demand for agile methods to rapidly learn how digital solutions can play a role in clinical practice. Clinical simulation is a pragmatic approach to generate evidence quickly by collecting data from end users as they perform tasks in realistic clinical scenarios. Two high-fidelity patient cases consisting of clinical notes, imaging reports and Floodlight™ MS data were developed with input from expert neurologists to explore clinical simulation as a method for evaluating Floodlight MS in routine multiple sclerosis (MS) care, such as identifying patient concerns and making care decisions.

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May 28 / Roche and Genentech
Real-World Clinical and Economic Outcomes Among Persons With Multiple Sclerosis Initiating First- Versus Second-Line Treatment With Ocrelizumab▼
Research has demonstrated that early use of ocrelizumab▼ (OCR), a high-efficacy disease-modifying therapy (DMT), can reduce relapses and delay progression, which is associated with reduced costs, in persons with multiple sclerosis (pwMS). However, there is limited real-world evidence on the impact of first-line OCR on clinical and economic outcomes. This study evaluated differences in events often associated with a relapse (EAR), healthcare resource use (HCRU), and costs among pwMS who initiated OCR as a first (1L) vs second or later line (2L+) DMT following MS diagnosis.
04:20 PM
Duration 20mins Gaylord Rockies Resort & Convention Center Summit 6-7
Long-term Efficacy of Satralizumab▼ in Adults With Aquaporin-4-IgG-seropositive (AQP4-IgG+) Neuromyelitis Optica Spectrum Disorder (NMOSD): Results from SAkuraMoon
Anthony Traboulsee, Ingo Kleiter, Jacqueline Palace, Kazuo Fujihara, Albert Saiz, Ivana Vodopivec, Gaelle Klingelschmitt, Carole Marcillat, Jeffrey L Bennett

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