Unmet needs in CLD and HCC

Around one in five people globally suffer from chronic liver disease,1 despite 90% of cases being preventable.2

This usually undetected disease silently progresses to HCC, the third leading cause of cancer death.3,4

If something doesn’t change, it is predicted that deaths from liver cancer will more than double by 2040.4

Roche’s ONE Liver mission is to break this cycle, to help stop, or even reverse the disease, and our ambition is to one day cure it.

Our core expertise will continue to focus on cutting-edge diagnostics and treatment. To enable greater impact, partnerships are key.

We want to work together with liver specialists, researchers and patient organisations on ambitious programmes across the disease continuum to prevent progression and ultimately save lives.


Learn more about unmet needs around:

CLD screening & diagnosis                                           

CLD treatment

HCC monitoring, surveillance & diagnosis                 

HCC prognosis & treatment




1. Cheemerla S. and Balakrishnan M. Clin Liver Dis (Hoboken) 2021;17:365–370.

2. Macpherson I, et al. Frontline Gastroenterol 2022;13:367–373.

3. McGlynn KA, et al. Hepatology 2021;73(Suppl 1):4–13.

4. Sung H, et al. CA Cancer J Clin 2021;71:209–249.

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