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Home Neuroscience Joint ACTRIMS-ECTRIMS meeting: MSToronto 2026
Roche and Genentech at

Joint ACTRIMS-ECTRIMS meeting: MSToronto 2026

October 21 - October 23
Toronto, Canada / Virtual (Hybrid)
mstoronto2026.org
We will be contributing to topics related to
Neuroscience
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Agenda
Medical Materials
01:00 PM
Duration 60mins Toronto, Canada
Impact of Ocrelizumab on Work Productivity, Healthcare Use and Caregiver Burden in Relapsing Multiple Sclerosis: Final Analysis of the MuSicalE Study
Maria Trojano, Vincent van Pesch, Raed Alroughani,Àlex Rovira, Gary Cutter, Athanasios Siadimas, Rakesh Kantaria, Licinio Craveiro, Sebastian Camerlingo, Jeremy Hobart
Neuroscience | Multiple Sclerosis

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Duration 60mins Toronto, Canada
Real-world treatment patterns and persistence with subcutaneous ocrelizumab in Denmark, Germany, and the United Kingdom
Melinda Magyari, Stefan Braune,Gillian Ingram, Finn Sellebjerg, Jeppe Romme Christensen, Peter Vestergaard Rasmussen, Henrik Boye Jensen, Sivagini Prakash, Morten Rytgaard, Arnfin Bergmann, James Witts, Owen R Pearson, Rod Middleton, Jana B. Jarecki, Yanic Heer, Ana Ferro, Sebastian Camerlingo, NTD Study group,
Neuroscience | Multiple Sclerosis

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Duration 60mins Toronto, Canada
Shorter Outpatient Visit Times for Patients With MS Treated With Subcutaneous Ocrelizumab Compared With Infused Anti-CD20 Disease-Modifying Therapies: A Retrospective Analysis of Electronic Health Records in the US
Kavita V. Nair, Arpamas Seetasith, Karina Raimundo, Katherine Brown, Mantas Dmukauskas, Megan Fiasconaro, Grace Leung
Neuroscience | Multiple Sclerosis

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Duration 60mins Toronto, Canada
A Phase II, Open-Label, Single-Arm Trial to Evaluate Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Fenebrutinib in Children and Adolescents With Relapsing Multiple Sclerosis (FENerations1): Study Design and Baseline Characteristics
Kumaran Deiva, Henry Sato, Katarzyna Kotulska, Geoff Powell, Yan Xu, Fei Tang, Ke Yang, Jon Lopez, Nisha Shah, Marina Ziehn, Ying-Fang Chen
Neuroscience | Multiple Sclerosis

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06:50 PM
Duration 10mins Toronto, Canada
Efficacy of Fenebrutinib vs Teriflunomide in Relapsing Multiple Sclerosis: Pooled Analysis Results From the FENhance 1 and 2 Studies
Maria Pia Sormani, Paul S. Giacomini, Mateus Boaventura, Fu-Dong Shi, Annette Okai, Ahmed Z. Obeidat, Finn Sellebjerg, Marquita Decker-Palmer, Anastasia Loukitcheva, Lilyan Wright, Nan Hu, Yoonha Choi, Katrin Madjar, Ann E. Herman, Christopher Harp
Neuroscience | Multiple Sclerosis

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08:30 PM
Duration 120mins Toronto, Canada
MuSicalE: Prognostic Value of Patient-Reported Outcomes in Predicting Ocrelizumab Discontinuation and Preservation of Clinical Status
Gary Cutter, Sebastian Camerlingo, Maria Trojano, Vincent van Pesch, Raed Alroughani, Àlex Rovira, Rakesh Kantaria, Licinio Craveiro, Jeremy Hobart
Neuroscience | Multiple Sclerosis

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Duration 120mins Toronto, Canada
B-Cell Reconstitution and Changes in Serum Neurofilament Light Chain During Pregnancy and Post Partum in Women Who Received Ocrelizumab: Results From the Prospective Phase IV MINORE Study
Riley Bove, Sandra Vukusic, Ruth Dobson, Kerstin Hellwig, Thomas F. McElrath, Celia Oreja-Guevara, Carlo Pietrasanta, Jens Kuhle, Agne Kazlauskaite, Licinio Craveiro, Chien-Ju Lin, Catarina Raposo, Noemi Pasquarelli, Tobias J. Derfuss
Neuroscience | Multiple Sclerosis

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10:30 PM
Duration 120mins Toronto, Canada
Longitudinal Analysis of Clinical Characteristics and Decision Drivers of Untreated People With Multiple Sclerosis in the German NeuroTransData (NTD) Real World Registry (2018–2024)
Stefan Braune, Yanic Heer, Carmen G. Berardo, Ana Ferro, Arnfin Bergmann, Juan Acosta, NTD Study Group, Martin Traber
Neuroscience | Multiple Sclerosis

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Duration 120mins Toronto, Canada
Real-World Effectiveness and Safety of First-Line Ocrelizumab Treatment in Early-Stage Relapsing Multiple Sclerosis
Tim Spelman, Raed Alroughani, Allan Kermode, Mario Habek, Tomas Kalincik, Dana Horakova, Anneke van Der Walt, William Brown, Gregor Brecl Jakob, Seyedmohammad Baghbanian, Serkan Ozakbas, Jeannette Lechner Scott, Radek Ampapa, Matteo Foschi, Cavit Boz, Julie Prévost, O. Gerlach, Simón Cárdenas-Robledo, Jose E Meca-Lallan, Emanuele D'amico, Richard MacDonell, Guy Laureys, Michael Barnett, Abdorreza Naser Moghadasi, Pamela McCombe, Juan Ignacio Rojas, Nevin A John, Nikolaos Grigoriadis, Davide Maimone, Inés González-Suárez, Yi Chao Foong, Katherine Buzzard, Beatriz Romero Ferrando, Mehmet Yetkin, Sara Eichau, Bassem Yammout, Ana Ferro, Erwan Muros-Le Rouzic, Licinio Craveiro, Helmut Butzkueven
Neuroscience | Multiple Sclerosis

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Duration 120mins Toronto, Canada
Plasma Cells, Myeloid, and Endothelial Cells At or Near Chronic Active Lesions Express MS Severity GWAS Genes Indicating Association with Progressive Biology
Tanuja Chitnis, Kalani Ratnasiri, Devin King, Alfredo Morales-Pinzon, Nicolas Strauli, Danielle Caefer, Michele Cavallari, Kyle C. Downer, Ethan Goodman, Aaron Grant, Ann Herman, Rihao Qu, Luke Xie, Jeffrey Hofmann, Tushar Bhangale, Akshaya Ramesh, Charles R.G. Guttmann, Xiaoming Jia
Neuroscience | Multiple Sclerosis

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Duration 60mins Toronto, Canada
Method comparison of the Roche Elecsys NfL and Siemens Atellica IM NfL assays for quantitative measurement of serum NfL
Alice Vidal, Michelle Nicholson, Clara Quijano-Rubio, Sabine Sellner, Maximilian Hastreiter, Yun- An Shen, Robert Müller, Dietmar Plonné
Neuroscience | Multiple Sclerosis

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08:30 PM
Duration 120mins Toronto, Canada
Impact of Ocrelizumab vs Fingolimod on Immune Function in Pediatric Patients With MS in the OPERETTA 2 Study
Amit Bar-Or, Barbara Kornek, Brenda Banwell, Chien-Ju Lin, Corinne Manlius, Fabien Bakdache, Filipe Palavra, Katarzyna Kotulska-Jozwiak, Kumaran Deiva, Liudmila Gearhart, Tammy Hennika, Tanuja Chitnis, Yun-An Shen
Neuroscience | Multiple Sclerosis

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Duration 120mins Toronto, Canada
Levels of Circulating B Cells and B Cell Subsets During Ocrelizumab Treatment in the CHIMES Trial of Black and Hispanic People With Multiple Sclerosis
Gregory Wu, Anne Cross, Anthony Reder, Craig Herrman, Ellen Mowry, Evanthia Bernitsas, Ibraheem Abioye, Jinglan Pei, Jugena Ndrio, Juzar Hooker, Kiel Telesford, Lilyana Amezcua, Mansoor Saleh, Mitzi Williams, Nancy Monson, Siddharama Pawate
Neuroscience | Multiple Sclerosis

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Duration 120mins Toronto, Canada
Vaccination and Disease-Modifying Therapies: Impact of Ocrelizumab vs Fingolimod on Preexisting Vaccine Seropositivity and Vaccine-Preventable Infections in Pediatric Patients With MS in OPERETTA 2
Brenda Banwell, Amit Bar-Or, Barbara Kornek, Chien-Ju Lin, Corinne Manlius, Fabien Bakdache, Filipe Palavra, Katarzyna Kotulska-Jozwiak, Kumaran Deiva, Liudmila Gearhart, Tammy Hennika, Tanuja Chitnis, Yun-An Shen
Neuroscience | Multiple Sclerosis

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Duration 120mins Toronto, Canada
OPERETTA 2: Continued Follow-Up of the Efficacy and Safety Profile of Ocrelizumab in Pediatric Relapsing-Remitting MS
Kumaran Deiva, Barbara Steinborn, Brenda Banwell, Carole Marcillat, Chien-Ju Lin, Corinne Manlius, Eduardo Vasconcellos, Leslie Benson, Miao Xu, Rafael Paterno, Romain Marignier, Tammy Hennika, Teri Schreiner, Tetyana Nehrych
Neuroscience | Multiple Sclerosis

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Duration 120mins Toronto, Canada
Long-Term Impact of First-Line Ocrelizumab Treatment in Early-Stage Relapsing-Remitting Multiple Sclerosis: Results From the 6-Year Phase III ENSEMBLE-LIBERTO Study
Robert A. Bermel, Gary R. Cutter, Rana Karabudak, Mark S. Freedman, Francesco Patti, Bruno Brochet, Ludo Vanopdenbosch, Ralph H.B. Benedict, Hans-Peter Hartung, Yuliang He, Héctor Lorenzo,Fabien Bakdache, Vanessa Di Felice, Licinio Craveiro, Joep Killestein
Neuroscience | Multiple Sclerosis

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Duration 120mins Toronto, Canada
Ocrelizumab Maintains Clinical and Safety Outcomes in Older Patients (>55 Years) With Progressive Multiple Sclerosis: 2-Year Results From the CONSONANCE Study
Helmut Butzkueven, Douglas Arnold, Amit Bar-Or, Ralph Benedict,Robert Bermel, Pavan Bhargava, Kathleen Blondeau, Declan Chard, Licinio Craveiro, Roland G. Henry, Owain Howell, Letizia Leocani, Marisa P. McGinley, Xavier Montalban, Finn Sellebjerg, Maria P.Sormani, Agne Kazlauskaite,Christine Lebrun-Frenay
Neuroscience | Multiple Sclerosis

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Duration 120mins Toronto, Canada
Comparing Serum Immunoglobulin G Trajectories Between Ocrelizumab and Ofatumumab: Real-World Evidence From a German Multiple Sclerosis Cohort
Stefan Braune, Niloofar Tavakoli, Inga Umbetova, Oliver Fasold, Johannes Fischer, Ralf Jankovits, Boris Kallmann, Thomas Knoll, Peter Kraft, Jürgen Kunz, Klaus Lehmann-Horn, Said Masri, Robert Pfister, Martin A. Schaller-Paule, Arnfin Bergmann, NTD Study Group, Yanic Heer, Mel Zuercher, Erwan Muros-Le Rouzic, Licinio Craveiro
Neuroscience | Multiple Sclerosis

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Duration 120mins Toronto, Canada
Sex Differences in Disease-Modifying Therapy Exposure Among Menopausal-Aged Adults With MS
Riley Bove, Divya Jain, Rongrong Wang, Noemi Pasquarelli, Erwan Muros-Le Rouzic, Arpamas Seetasith, Elmor D. Pineda
Neuroscience | Multiple Sclerosis

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Duration 120mins Toronto, Canada
No Evidence of Disease Activity With Fenebrutinib vs Teriflunomide in Relapsing Multiple Sclerosis: Results From the Phase III FENhance 1 and 2 Trials
João José Fernandes Cardoso Araújo Cerqueira, Jelena Drulovic, Christine Lebrun-Frenay, Tjalf Ziemssen, Marquita Decker-Palmer, Anastasia Loukitcheva, Stephanie Son, Claude Berge, Katrin Madjar, Nicolas Lindau, Monika Adamczyk-Sowa
Neuroscience | Multiple Sclerosis

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Duration 120mins Toronto, Canada
Fenebrutinib Reduces CSF Microglial and Astrocyte Biomarkers Expressed at or Near Chronic Active Rim Lesions in Patients With RMS or PPMS
Amit Bar-Or, Christopher Harp, Jenny Jiang, Katrin Madjar, Enrique Alvarez, João Cerqueira, Rebecca S. Farber, Freddy Guillermo Castro Farfán, Ho Jin Kim, Enric Monreal, Luisa María Villar, Martin S. Weber, Esther Nie, Shristi Pandey, Dwight F. Newton, Xiaoming Jia, Akshaya Ramesh, Ann E. Herman, Finn Sellebjerg
Neuroscience | Multiple Sclerosis

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Duration 60mins Toronto, Canada
Quality of shared decision-making in early relapsing-remitting multiple sclerosis: results from the AGA-25 questionnaire
Inés González-Suárez, Elena García-Arcelay, Jacobo Caruncho, Antonio Candeliere-Merlicco, Aida Orviz, Jesús Martín-Martínez, Raquel Piñar, Elena Álvarez-Rodríguez, Eva Pacheco, Laura Borrega, Ignacio Casanova, Ana B Caminero, José L Sánchez-Menoyo, Montserrat Gómez-Gutiérrez, Olga Carmona, Carmen Calles, Miguel A Hernández, Pablo López-Muñoz, Jorge Mauriño, Ángel Pérez-Sempere
Neuroscience | Multiple Sclerosis

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Duration 120mins Toronto, Canada
Predictors of High Fear of Relapse in Patients with Early- Stage Relapsing-Remitting Multiple Sclerosis
Ángel Pérez-Sempere, Elena García-Arcelay, Jacobo Caruncho, Antonio Candeliere-Merlicco, Aida Orviz, Jesús Martín-Martínez, Raquel Piñar, Elena Álvarez-Rodríguez, Eva Pacheco, Laura Borrega, Ignacio Casanova, Ana B Caminero, José L Sánchez-Menoyo, Montserrat Gómez-Gutiérrez, Olga Carmona, Carmen Calles, Miguel A Hernández, Pablo López-Muñoz, Jorge Mauriño, Inés González-Suárez
Neuroscience | Multiple Sclerosis

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Duration 120mins Toronto, Canada
Age-adjusted Elecsys NfL reference percentiles and Z-scores for insights on disease activity in relapsing-remitting multiple sclerosis
Michael Khalil, Paula Lopez-Gamundi, Galina Babitzki, Isabelle Schrurs, Clara Quijano‑Rubio, Deirdre Allegranza, Sabine Sellner, Alice Vidal, Pascal Benkert, Jens Kuhle
Neuroscience | Multiple Sclerosis

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03:05 PM
Duration 10mins Toronto, Canada
Fenebrutinib Shows a Therapeutic Effect on MS Progressive Biology: Outcomes on Paramagnetic Rim Lesions and Slowly Expanding Lesions in the Phase III FENhance I/II and FENtrepid Trials in Relapsing and Primary Progressive Multiple Sclerosis
Jiwon Oh, Robert Carruthers, Olga Shulga, Robert T. Naismith, Douglas L. Arnold, Dan Ontaneda, Esther Nie, Louise Roberts, Jon Lopez, Nan Hu, Katrin Madjar, David Clayton, Finn Sellebjerg
Neuroscience | Multiple Sclerosis

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