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Home SABCS 2023
Roche and Genentech at

SABCS 2023

December 05 - December 09
San Antonio, USA
sabcs.org
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Medical Materials
Agenda
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03:30 PM
Duration 15mins Hall 1
Adding atezolizumab to adjuvant chemotherapy for stage II and III triple-negative breast cancer is unlikely to improve efficacy: interim analysis of the ALEXANDRA/IMpassion030 phase 3 trial
Ignatiadis M et al.
Oncology | Breast Cancer

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06:00 PM
Duration 120mins San Antonio, USA
Circulating tumor DNA dynamics in acelERA Breast Cancer: a Phase II study of giredestrant for estrogen receptor-positive, HER2-negative, previously treated advanced breast cancer
Collier A, Bardia A, Sohn J, Lim E, Chavez-MacGregor M, Martin M, Martinalbo J, Pérez-Moreno P.D, Moore H
Oncology | Breast Cancer

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11:00 PM
Duration 120mins San Antonio, USA
Risk of anaphylaxis associated with the use of pertuzumab or other biologics with potential for use outside the hospital
Sanglier T, Chambers T, Harton J, Wahyudi L.A, Genevray M, Restuccia E, Droz-Perroteau C, Dang C.T
Oncology | Breast Cancer

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Duration 120mins San Antonio, USA
INAVO122: a Phase III study of maintenance inavolisib or placebo + pertuzumab + trastuzumab following induction with pertuzumab + trastuzumab + a taxane in patients with PIK3CA-mutated, HER2-positive advanced breast cancer
Swain S.M, Barrios C.H, Basho R, Curigliano G, Harbeck N, Huang C-S, Loi S, Turner N.C, Chen J, Henschel V, Warburton S, Amair-Pinedo F, Cortés J
Oncology | Breast Cancer

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Duration 120mins San Antonio, USA
INAVO121: Phase III study of inavolisib + fulvestrant vs alpelisib + fulvestrant in patients with hormone receptor-positive, HER2-negative, PIK3CA mutated locally advanced or metastatic breast cancer
Juric D, Kalinsky K.M, Im S-A, Ciruelos E, Bianchini G, Barrios C.H, Jacot W, Schmid P, Loi S, Rugo H.S, Craine V, Huchinson K.E, Flechais A, Thanopoulou E, Harbeck N
Oncology | Breast Cancer

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01:00 PM
Duration 60mins San Antonio, USA
Brain metastases in metastatic breast cancer: prevalence per line of treatment and cumulative incidence in a cohort of 18075 real-world patients
Sammons S.L, Leone J.P, Sanglier T, Lambert P, Montemurro F, Poppe R, Restuccia E, Tolaney SM, Lin NU
Oncology | Breast Cancer

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Duration 60mins San Antonio, USA
MORPHEUS Hormone Receptor-Positive Breast Cancer: interim analysis of a Phase Ib/II study of fulvestrant ± atezolizumab and abemaciclib triplet treatment in patients with metastatic disease
Jung KH, Im S-A, Yardley D, Hurvitz SA, Lee KS, Sonnenblick A, Shachar S, Tan AR, Comen E, Gal-Yam E, Brufsky AM, Rugo HS, Zhu J, Bader E, DuPree K, Cahuzac C, Young F, Schwab R, Cha E, Telli ML
Oncology | Breast Cancer

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06:00 PM
Duration 120mins San Antonio, USA
ASTEFANIA: a Phase III study of ado-trastuzumab emtansine plus atezolizumab or placebo as adjuvant therapy in patients with residual invasive breast cancer after neoadjuvant HER2-targeted therapy and chemotherapy
Schmid P, Bachelot T, Bianchini G, Harbeck N, Loi S, Park Y.H, Prat A, Gilham L, Boulet T, Gochitashvili N, Monturus E, Lambertini C, Nyawira B, Knott A, Hurvitz S.A
Oncology | Breast Cancer

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11:00 PM
Duration 120mins San Antonio, USA
Exposure–response analyses of GO39932: a Phase Ia/b study of giredestrant in estrogen receptor-positive, HER2-negative, locally advanced or metastatic breast cancer
Jhaveri K, Lien YT, Turner N.C, Lim E, Cannon M, Anziano R, Langenhorst J, Yoshida K, Malhi V, Gates M.R, Eng-Wong J, Li C, Shah M.D, Pérez-Moreno P.D, Yu J, Bardia A
Oncology | Breast Cancer

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01:00 PM
Duration 60mins San Antonio, USA
Interim analysis of giredestrant + inavolisib in MORPHEUS Breast Cancer: a Phase Ib/II study of giredestrant treatment combinations in estrogen receptor-positive, HER2-negative, locally advanced/metastatic breast cancer
Rugo H.S, Gion Cortès M, Hernando C, Jung K.H, Oliveria M, Telli M.L, Vidal G, Vatandoust S, Zhu J, Schwab R, Ngo H.X, Ferreira E, Collier A, Cahuzac C, Gal-Yam E
Oncology | Breast Cancer

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Duration 60mins San Antonio, USA
Key drivers of therapeutic response and resistance to giredestrant from GO39932: a Phase Ia/b study in patients with estrogen receptor-positive, HER2 negative, locally advanced or metastatic breast cancer
Liang J, Ong C, Giltnane J.M, Aimi J, Chang C-W, Gates M.R, Eng-Wong J, Pérez-Moreno P.D, Jhaveri K.L, Lim E, Turner N.C, Moore H.M
Oncology | Breast Cancer

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05:00 PM
Duration 180mins Hall 1
Phase III study of adjuvant ado-trastuzumab emtansine vs trastuzumab for residual invasive HER2-positive early breast cancer after neoadjuvant chemotherapy and HER2-targeted therapy: KATHERINE final IDFS and updated OS analysis
Loibl S, Mano MS, Untch M, Huang C-S, Mamounas EP, Wolmark N, Knott A, Siddiqui A, Boulet T, Nyawira B, Restuccia E, Geyer Jr CE
Oncology | Breast Cancer

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05:15 PM
Duration 180mins Hall 1
Inavolisib or placebo in combination with palbociclib and fulvestrant in patients with PIK3CA-mutated, hormone receptor-positive, HER2-negative locally advanced or metastatic breast cancer: Phase III INAVO120 primary analysis
Komal L. Jhaveri
Oncology | Breast Cancer

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