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WCLC 2024

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Sep 10 / Roche and Genentech
LCMC3: Long-term disease-free and overall survival and their association with ctDNA after neoadjuvant atezolizumab for NSCLC
LCMC3 is a Phase II trial that evaluated the safety and efficacy of neoadjuvant atezolizumab followed by optional adjuvant atezolizumab and/or chemo in patients with early-stage, resectable NSCLC. This presentation reports the final disease-free survival and overall survival results and their association with ctDNA status and clearance in the LCMC3 study.

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Sep 9 / Roche and Genentech
Divarasib single-agent long-term follow-up and atezolizumab combination treatment in patients with KRAS G12C-positive NSCLC
Long-term follow-up phase 1 data of divarasib single-agent, and safety and efficacy of divarasib in combination with atezolizumab, in patients with KRAS G12C-positive NSCLC.

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Sep 9 / Roche and Genentech
Divarasib versus Adagrasib or Sotorasib in Pretreated KRAS G12C+ Advanced or Metastatic Non-Small Cell lung Cancer (NSCLC)
Trial-in-progress poster presenting the study design and objectives of the Phase III Krascendo 1 trial of divarasib versus adagrasib or sotorasib in advanced/metastatic KRAS G12C+ NSCLC.
07:00 PM
Duration 2hrs San Diego, USA
An evidence-driven approach to optimising clinical, operational, and economic value in the lung cancer care pathway
Margarita Majem, Ivana Gabriela Sullivan, Alfons Torrego, Jordi Surrallés, John Purdy, Marina Ascorbe Carmona, Harry Dunsford, Matthias Wubs

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05:00 PM
Duration 2hrs San Diego, USA
Exploring circulating tumor antigens as a faster and lower cost alternative to circulating tumor DNA in IMpower150
Namrata S Patil

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05:57 PM
Duration 10mins 20A
IMpower010 5-y subgroup analysis and relapse patterns: Phase 3 study of atezolizumab vs BSC in stage II-IIIA NSCLC
Felip E, Wakelee HA, Vallieres E, Martinez-Marti A, Goloborodko O, Zhou C, Rittmeyer A, Chella A, Reck M, Csoszi T, Bondarenko I, Kenmotsu H, Shutte W, Ding B, Zhu C, Ballinger M, Bennett E, Gitlitz BJ, Altorki N

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01:15 AM
Duration 90mins San Diego, USA
LCMC3: Clinical Utility of SUVmax on Preoperative 18F-FDG PET-CT in Resectable NSCLC Treated with Neoadjuvant Atezolizumab
B Merritt, D Carbone, E Toloza, J Lee, A Patterson, V Rusch, B Johnson, P Bunn, K Schulze, A Nicholas, A Johnson, D Owen

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10:00 AM
Duration 2hrs San Diego, USA
Divarasib versus Adagrasib or Sotorasib in Pretreated KRAS G12C+ Advanced or Metastatic Non-Small Cell lung Cancer (NSCLC)
Shirish M. Gadgeel, Uyi Osaghae, Ahmadur Rahman, Tharu M. Fernando, Mark T. Lin, Kalpesh Koli, Christoph Meyenberg, Michael Mathisen, Ferdinandos Skoulidis

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10:30 PM
Duration 45mins 20A
ALINA Safety Results: Adjuvant Alectinib vs Chemotherapy in Patients with Resected ALK+ Non-Small Cell Lung Cancer (NSCLC)
Hidehito Horinouchi, Benjamin J. Solomon, Yi-Long Wu, Fabrice Barlesi, Makoto Nishio, Jin Seok Ahn, Dae Ho Lee, Jong-Seok Lee, Wenzhao Zhong, Maximilian Hochmair, Igor Bondarenko, David Planchard, Achim Rittmeyer, Beiying Ding, Thorsten Ruf, Leah Adler, Astrid Scalori, Rafal Dziadziuszko

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Duration 45mins 20D
Divarasib single-agent long-term follow-up and atezolizumab combination treatment in patients with KRAS G12C-positive NSCLC
Sacher A, Wilson H. Miller Jr., Luis Paz-Ares, Myung-Ju Ahn, Manish R. Patel, Rafal Dziadziuszko, Armando Santoro, Jia Luo, Ben Markman, Pierre Freres, Marloes Van Dongen, Jayesh Desai, Samantha Bowyer, Andres Cervantes, Josiane Mourão Dias, Alejandro Falcon, Matthew G. Krebs, Scott Laurie, Hans Prenen, Ruth Perets, Erminia Massarelli, Se Hyun Kim, Maria De Miguel, Sanjeev Deva, Elena Garralda, Laura Medina, João Daniel Guedes, Salvatore Siena, Tormod Guren, Eugenio Fernandez, Loes Latten Jansen, Rita De Cassia Costamilan, Yoonha Choi, Sandhya Mandlekar, Mark T. Lin, Kenneth K. Yau, Julie Chang, Stephanie Royer-Joo, Tomi Jun, Neekesh V. Dharia, Jennifer L. Schutzman, Patricia Lorusso

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10:35 PM
Duration 75mins 20A
LCMC3: Long-term disease-free and overall survival and their association with ctDNA after neoadjuvant atezolizumab for NSCLC
D H. Owen, J E. Chaft, E B. Haura, E Toloza, S N. Waqar, G. A Patterson, D Finley, J Blasberg, D Raz, R Salgia, J M. Lee, P Bunn, I Wistuba, D J. Kwiatowski, F Hirsch, A Gopalakrishnan, A Batra, E Brandao, J Grindheim, A Nicholas, A Johnson, K Schulze, E Shum, M Nagasaka, J Gainor, C J. McNamee, B E. Johnson, M G. Kris, V W. Rusch, D P. Carbone

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