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2025 ASCO® Annual Meeting

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01:42 PM
Duration 6mins United States
Fixed duration subcutaneous (SC) mosunetuzumab▼ (Mosun) in patients with previously untreated high-tumor burden follicular lymphoma (FL): interim results from the Phase II MorningSun study
Flinn IW, Burke JM, Sharman JP, Anz B, Zuniga R, Tun AM, Jani P, Biondo JML, Wu M, Mun Y, Chopra VS, Farighi R, Lin T, Villasboas JC, Budde LE

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02:00 PM
Duration 180mins Chicago, USA
Updated Efficacy and Safety of Entrectinib▼ in Children with Extracranial Solid or Primary Central Nervous System (CNS) Tumors Harboring ROS1 Fusions
A. Desai, H. Wang, E. Basu, M. Casanova, A. Armstrong, D. Morgenstern, C. Pratilas, A. Cardenas, T. Barata, C. E. Devlin, K. E. Hutchinson, F. Wu, J. Wulff, A. Gajjar, E. Fox

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Duration 180mins Chicago, USA
Risk factors (RF) for brain metastases (BM) in patients (pts) with metastatic breast cancer (MBC): An analysis of US electronic health records (EHRs)
Leone JP, Sammons S.L, Lamert P, Huang Y, Montemurro F, Shivhare M, Restuccia E, Knott A, Sanglier T, Tolaney S.M, Lin N.U

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Duration 180mins Chicago, USA
Preliminary Safety, Pharmacokinetics, and Clinical Activity of Mosperafenib (RG6344) in Patients with BRAF V600E-mutant Metastatic Colorectal Cancer
E. Fontana, M. Vieito, E. Castanon, I. Matos, O. Bechter, I. Moreno, C. Han, RL. Eefsen, DJ. Pinato, R. Plummer, H. Prenen, G. Schnetzler, P. Pettazzoni, D. Dejardin, A. Keelara, E. Cinato, N. Flinn, NA. Kratochwil, A. Roller, N. Keshelava

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Duration 6mins United States
Glofitamab▼ plus gemcitabine and oxaliplatin (Glofit-GemOx) in patients (pts) with relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL): 2 year (yr) follow up of STARGLO
Abramson JS, Ku M, Hertzberg M, Fox CP, Herbaux C, Huang H-Q, Yoon DH, Kim WS, Zhang H, Abdulhaq H, Townsend W, Mulvihill E, Orellana-Noia V, Ta R, Huang H, Kallemeijn M, Belousov A, Bottos A, Lundberg L, Gregory G

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06:30 PM
Duration 180mins Chicago, USA
Krascendo 2: a phase III study of divarasib and pembrolizumab vs pembrolizumab and chemotherapy in patients with previously untreated, advanced or metastatic, KRAS G12C-mutated non-small cell lung cancer (NSCLC)
Skoulidis F, Solomon B, Popat S, Frost N, Heist R, Zhou C, Zarak Crnkovic M, Antic V, Prizant H, Mayo MC Meyenberg C, Keufer-Le Gall S

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Duration 180mins Chicago, USA
IMpower010: Genomic Profiling and Clinical Outcomes With Adjuvant Atezolizumab in Early-Stage Non-Small Cell Lung Cancer (eNSCLC)
Heather A. Wakelee, Enriqueta Felip, Caicun Zhou, Eric Vallières, Martin Reck, Nasser Altorki, Achim Rittmeyer, Tibor Csoszi, Ihor Vynnychenko, Antonio Chella, Velimir Gayevskiy, Wei Zou, Barbara Gitlitz, Marcus Ballinger, Elizabeth Bennett, Barzin Y. Nabet, Minu K. Srivastava

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07:19 PM
Duration 12mins United States
Phase I/Ib study of inavolisib (INAVO) alone and in combination with endocrine therapy ± palbociclib (PALBO) in patients (pts) with PIK3CA-mutated, hormone receptor-positive, HER2-negative locally advanced/metastatic breast cancer (HR+, HER2- LA/mBC): Analysis of hyperglycemia (HG) in prediabetic/obese pts
Oliveira M, Accordino M, Cervantes A, Gambardella V, Hamilton E, Italiano A, Jhaveri K, Juric D, Kalinsky K, Krop I, Saura C, Schmid P, Turner N C, Varga A, Jin Y, Lim S, Royer-Joo S, Shankar N, Schutzman J, Bedard P

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12:00 PM
Duration 12mins United States
Randomized trial of standard chemotherapy alone or combined with atezolizumab as adjuvant therapy for patients with stage III deficient DNA mismatch repair (dMMR) colon cancer (Alliance A021502; ATOMIC)
Frank A. Sinicrope, Fang-Shu Ou, Dirk Arnold, Walter Peters, Robert J. Behrens, Christopher H. Lieu, Khalid Matin, Deirdre J. Cohen, Samara L. Potter, Wendy L. Frankel, Ardaman Shergill, Dennis Hsu, Anke C. Reinacher-Schick, Tyler Zemla, Clare A. Gatten, Eileen M. O'Reilly, Jeffrey A. Meyerhardt

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02:00 PM
Duration 180mins Chicago, USA
Meeting diversity enrollment targets in IMbrave152/SKYSCRAPER-14, a global phase 3 study in patients with unresectable hepatocellular carcinoma (HCC)
Cotter C, Bhagat R, Bulhan H, Leon P, Lin L, Richie N, Sims R, Spahn J, Stamatis M, Yalovsky L, Zhu H, Ibrahim Y

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Duration 180mins Chicago, USA
Longitudinal Assessment From Liquid Biopsy of Mutations in CD20: A Pilot Study Using a PETE Enrichment Strategy
Tyler Landrith, Linlin Cao, Samantha Smith, Ruben van der Merwe, Corinna Lutterbeck, Carmelo Carlo-Stella, Michael J Dickinson, Martin Hutchings, Ulrich Schlecht, Antonio Sorrentino, Wei Yang, Patrick Bogard, Marina Bacac, Alessia Bottos

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02:00 PM
Duration 180mins Chicago, USA
Giredestrant (G) with atezolizumab (ATEZO), and/or abemaciclib (ABEMA) in patients (pts) with ER+/HER2- locally advanced/metastatic BC (LA/mBC): Interim analysis (IA) from the phase I/II MORPHEUS Breast Cancer (BC) study
Oliveira M, Sonnenblick A, Stemmer S, Cortes Gion M, Im SAH, Bermejo De Las Heras B, Gal Yam E, Sohn JH, Wander S, Rugo HS, Park Y, Cahuzac C, Collier A, Ngo H, Retiere AC, Schwab R, Zhu J, Jung KH

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Duration 180mins Chicago, USA
Phase Ib study of inavolisib (INAVO) + weekly paclitaxel (wP) in patients (pts) with locally advanced/metastatic (LA/m) incurable solid tumors: Safety, pharmacokinetics (PK), and preliminary antitumor activity
S.A. IM, G. Alonso Casal, I. Moreno, R. Kristoffer, V. Gambardella, A. Italiano, S. Lim, S. Cheeti, P. Yu, A. Swat, F. Amair-Pinedo, D. Juric

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06:30 PM
Duration 180mins Chicago, USA
Impact of proton pump inhibitor (PPI) pharmacogenomics (PGx) on toxicities associated with immune checkpoint inhibitor (ICI) therapy
Kennedy LC, Mohindra R, Sharpe JM, Mycroft SL, Balko JM, Chandler SG, Lyalina S

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10:00 PM
Duration 12mins Arie Crown Theater
Lurbinectedin + atezolizumab as first-line maintenance treatment in patients with extensive-stage small cell lung cancer: Primary results of the Phase 3 IMforte trial
L Paz-Ares, H Borghaei, S Liu, S Peters, R Herbst, K Stencel, M Majem, G Czyzewic, R Bernabe Caro, K H Lee, M Johnson, N Karadurmus, C Grohe, V Cuchelkar, V Graupner, M Kaul, L Lin, D Chakrabarti, K Bhatt, M Reck

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