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Leukemia & Lymphoma

Lymphoma is the most common type of blood cancer, with over 400,000 people diagnosed around the world each year.

It begins in a certain type of cell of the immune system (lymphocytes, or white blood cells) and can be divided into two main categories – Hodgkin lymphoma, and Non-Hodgkin lymphoma (NHL).

NHL is the more common of the two and can be further categorised as indolent (slow growing) or aggressive (fast growing), depending on the speed with which the cancer grows. Follicular lymphoma is the most common indolent form of the disease and diffuse large B-cell lymphoma (DLBCL) is the most common aggressive form.

Leukaemia is the second most common form of blood cancer, with over 300,000 people diagnosed globally each year. The type of leukaemia that a person has is dependent on which type of blood cell – white or red – becomes cancerous.

The four main types of leukaemia include acute lymphocytic leukaemia (ALL), chronic lymphocytic leukaemia (CLL), acute myeloid leukaemia (AML), and chronic myeloid leukaemia (CML).

Learn more about the latest advances in Roche lymphoma and leukaemia research.

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Jul 4 / Roche and Genentech
Burden of Illness in Patients with Higher-risk Myelodysplastic Syndromes by Baseline Transfusion Status
A retrospective observational study using the SEER-Medicare linked database to better understand the transfusion burden in patients with higher-risk myelodysplastic syndromes at baseline and how this burden is impacted post-HMA initiation, as well as the healthcare resource utilization and costs amongst these patients post-HMA initiation, according to baseline transfusion status.

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Jul 7 / Roche and Genentech
Clinical Evaluation of Somatic Genomic Alteration Annotation for Hematological Malignancies using NAVIFY® Tertiary Analysis Software
The NAVIFY® Mutation Profiler is a CE-marked, cloud-based tertiary analysis software that provides curation, annotation, and reporting of somatic genomic alterations and biomarker signatures identified by NGS (next-generation sequencing). This poster shows the results of a clinical evaluation study validating the accuracy and reproducibility of the NMP software and curation process across a panel of hematologic malignancies.

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Jun 11 / Roche and Genentech
Obinutuzumab plus chemotherapy demonstrates long-term benefit over rituximab plus chemotherapy in patients with previously untreated follicular lymphoma: final analysis of the GALLIUM study
GALLIUM is a Phase III, randomized study of obinutuzumab-based immunochemotherapy versus rituximab-based immunochemotherapy in patients with previously untreated advanced indolent non-Hodgkin lymphoma. Here we report the results of the final analysis in patients with follicular lymphoma after eight years of follow-up.

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Jun 10 / Roche and Genentech
Clinical outcomes in patients with higher-risk myelodysplastic syndromes receiving hypomethylating agents: A large population-based analysis
A large population-based analysis, using the SEER-Medicare linked database, to understand the survival outcomes and progression-related events of older patients (aged ≥66 years) treated with azacitidine or decitabine for higher-risk-MDS in the USA.

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Independent content
Jan 7 / Springer Healthcare
ASH 2021 In-Depth Report: Lymphoma
This ASH 2021 in-depth report provides an update on recent advances in the management of aggressive and indolent lymphomas.

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Independent content
Jan 7 / Springer Healthcare
ASH 2021 In-Depth Report: Leukaemia
This ASH 2021 in-depth report provides an overview of the aetiology and treatment of leukaemia.
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