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Roche and Genentech at

2025 ASCO® Gastrointestinal Cancers Symposium

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Personalised Healthcare
Jan 24 / Roche and Genentech
Real-world (RW) experience with atezolizumab + bevacizumab (A+B) for the treatment of unresectable hepatocellular carcinoma (uHCC): A multicenter study
A+B is the preferred first-line (1L) standard of care for uHCC, with emerging Real World evidence supporting its use in a broad patient (pt) cohort. This poster reports on the evaluated pt characteristics, clinical and treatment outcomes in pts treated at five U.S. institutions: Mayo Clinic, Houston Methodist, Moffitt Cancer Center, Mays Cancer Center, and University of Arizona.

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Jan 24 / Roche and Genentech
KIRROS: A phase II trial in progress of first-line atezolizumab (atezo) with or without bevacizumab (bev) in patients with unresectable hepatocellular carcinoma (HCC) and Child-Pugh B (CPB) cirrhosis
This poster presents the background and study design for the prospective, open-label, multicohort, multicenter Phase II KIRROS trial, which will evaluate the safety and efficacy of first-line atezolizumab plus bevacizumab in participants with unresectable hepatocellular carcinoma (HCC) and Child-Pugh B cirrhosis.
07:30 PM
Duration 90mins San Francisco, USA
KIRROS: A phase II trial in progress of first-line atezolizumab (atezo) with or without bevacizumab (bev) in patients with unresectable hepatocellular carcinoma (HCC) and Child-Pugh B (CPB) cirrhosis
Kristen Spencer, Amit Singal, Laura Kulik, Augusto Villanueva, Renuka Iyer, Shilpa Chakalakal, Rucha Kothari, Jinnie Ko, Norelle Reilly, Thomas Stark, Anthony El-Khoueiry

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Duration 90mins San Francisco, USA
Real-world (RW) experience with atezolizumab + bevacizumab (A+B) for the treatment of unresectable hepatocellular carcinoma (uHCC): A multicenter study
Maen Abdelrahim1, Abdullah Esmail1, Richard D. Kim2, Sukeshi Patel Arora3, Junaid Arshad4, Ioannis A. Kournoutas5, Conor D. O’Donnell5, Todor I. Totev6, Amie Tan7, Fan Mu6, Shravanthi M. Seshasayee6, Sairy Hernandez7, Nguyen H. Tran5

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