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Home Oncology ESMO 2025
Roche and Genentech at

ESMO 2025

October 17 - October 21
Berlin, Germany
esmo.org
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Medical Materials
Agenda
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12:10 PM
Duration 10mins Hamburg Auditorium
SKYSCRAPER-07: A phase III, randomized study of atezolizumab (atezo) with or without tiragolumab (tira) in patients (pts) with unresectable esophageal squamous cell carcinoma (ESCC) that has not progressed following definitive concurrent chemoradiotherapy (dCRT)
Amy Cai, Anthony Turpin, Baosheng Li, Byoung Chul Cho, Chih-Hung Hsu, Edward Cha, Florian Lordick, Ian Chau, Jianxin Fan, Karyn Goodman, Li Zhang, Lucjan Wyrwicz, Luhua Wang, Manish Shah, Ming Huang Chen, Muro Kei, Qiong Wu, Rui-Hua Xu, Sarah Kim, Shegan Gao
Oncology | Esophageal Squamous Cell Carcinoma

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03:00 PM
Duration 5mins Heidelberg Auditorium
Single-agent divarasib experience in patients with KRAS G12C-positive pancreatic adenocarcinoma (panc), cholangiocarcinoma (cholangio), and other solid tumors
Krebs M.G.
Oncology | Pancreatic Cancer

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03:10 PM
Duration 10mins Berlin Auditorium
Final overall survival (OS) and safety data in patients with previously untreated, advanced ALK-positive (ALK+) non-small cell lung cancer (NSCLC) from the ALEX study
Tony Mok
Oncology | Non-Small Cell Lung Cancer

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07:00 AM
Duration 60mins Berlin, Germany
ESMO treatment (tx) guideline adherence in patients (pts) with lung cancer (LC) with EGFR or ALK (EGFR/ALK) alterations: a WAYFIND-R registry-based study
Dienstmann R.
Oncology | Lung Cancer

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07:25 AM
Duration 10mins Bonn Auditorium
SKYSCRAPER-03: Phase 3, open-label, randomised study of atezolizumab + tiragolumab vs durvalumab in locally advanced, unresectable, stage III non-small cell lung cancer after platinum-based concurrent chemoradiation
Rafal Dziadziuszko
Oncology | Non-Small Cell Lung Cancer

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08:15 AM
Duration 10mins Berlin Auditorium
Giredestrant, an oral selective oestrogen receptor antagonist and degrader, in combination with everolimus in patients with ER-positive, HER2-negative advanced breast cancer (ER+, HER2– aBC) previously treated with a CDK4/6 inhibitor (i): Primary results of the Phase III evERA BC trial
Erica Mayer
Oncology | Her2 Negative Breast Cancer

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10:00 AM
Duration 45mins Berlin, Germany
IMscin001 final analysis: a randomised phase 3 study of subcutaneous (SC) versus intravenous (IV) atezolizumab (atezo) in patients with locally advanced or metastatic non- small cell lung cancer (NSCLC)
Enriqueta Felip, Fiona Young, Luis Herraez-Baranda, Mauricio Burotto, Nadia Tosti, Renzo Alvarez, Teresa Barata, Yotsawaj Runglodvatana, Yovanna Castro, Zanete Zvirbule
Oncology | Non-Small Cell Lung Cancer

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Duration 45mins Berlin, Germany
Machine learning classification of small cell lung cancer using plasma multiomics in IMPower133
M. Reck
Oncology | Small Cell Lung Cancer

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03:15 PM
Duration 5mins Hamburg Auditorium
Patterns of disease progression (PD) and efficacy associated with tumour burden from the Phase 3 IMforte study of lurbinectedin (lurbi) + atezolizumab (atezo) as first-line (1L) maintenance treatment (tx) in ES-SCLC
Paz Ares
Oncology | Small Cell Lung Cancer

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08:55 AM
Duration 10mins Berlin Auditorium
IMbrave152/SKYSCRAPER-14: a phase III study of first-line tiragolumab + atezolizumab + bevacizumab vs placebo + atezolizumab + bevacizumab for patients with untreated locally advanced or metastatic hepatocellular carcinoma
R. Finn
Oncology | Hepatocellular Carcinoma

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10:00 AM
Duration 45mins Berlin, Germany
Safety of atezolizumab with or without tiragolumab following neoadjuvant chemoradiotherapy in patients with locally advanced rectal cancer (NEOTERIC Study): a randomized, open-label phase II study
Xu J.
Oncology | Rectal cancer

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Duration 45mins Berlin, Germany
Phase I study of ERY974 + atezolizumab (atezo) + bevacizumab (bev) in patients with locally advanced or metastatic hepatocellular carcinoma (HCC)
Ann-Lii Cheng Hideki Ueno, Sadahisa Ogasawara, Chia-Jui Yen, Masatoshi Kudo, Teng-Yu Lee, Masafumi Ikeda, Yin-Hsun Feng, Chao-Hung Hung, Makoto Ueno, Daisuke Shimizu, Hitomi Takeshita, Hiroaki Tomita, Mikiko Nakamura, Chika Ogami, Chun-Yen Lin
Oncology | Hepatocellular Carcinoma

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Duration 45mins Berlin, Germany
Clinical outcome of patients with sporadic vs Lynch syndrome-related stage III colon cancers with deficient mismatch repair (dMMR) treated in a randomized trial of adjuvant FOLFOX alone or combined with atezolizumab (Alliance A021502; ATOMIC)
Sinicrope F.A.
Oncology | Colorectal Cancer

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11:00 AM
Duration 90mins Berlin, Germany
Navigating tailored combination treatments in HR+ mBC
Hope S. Rugo, Giampaolo Bianchin, Frederique Penault-Llorca, Stephen Chia
Oncology | Breast Cancer

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02:45 PM
Duration 5mins Cologne Auditorium
SKYSCRAPER-09: Phase 2, non-comparative, randomised study of tiragolumab + atezolizumab and placebo + atezolizumab as first-line treatment in patients with recurrent/metastatic PD-L1+ squamous cell carcinoma of the head and neck(atezo) and atezo + placebo (pbo) as first-line (1L) treatment in patients (pts) with recurrent/metastatic PD-L1+ squamous cell carcinoma of the head and neck (R/M SCCHN)
Amanda Psyrri, Amaury Daste, Arunee Dechaphunkul, Ching-Yun Hsieh, Chipman R Stroud, Christina Matheny, Christophe Le Tourneau, Deborah Wong, Denise Bradley (Richardson), Floriane Alias, JEROME FAYETTE, Kevin Harrington, Maura Gillison, Melissa Johnson, Nuttapong Ngamphaiboon, Se Hoon Lee, Tien Hoang, Wei Zhang, Yibing Yan
Oncology | Squamous Cell Cancer

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10:00 AM
Duration 45mins Berlin, Germany
Phase I/Ib trial of inavolisib▼ (INAVO) + pertuzumab (P) + trastuzumab (H) for PIK3CA-mutated (mut), HER2-positive advanced breast cancer (HER2+ aBC)
Philippe L. Bedard
Oncology | Breast Cancer

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Duration 45mins Berlin, Germany
Interim analysis of giredestrant (GIRE) + inavolisib (INAVO) in MORPHEUS Breast Cancer (BC): A Phase Ib/II study of GIRE treatment (rx) combinations in patients (pts) with estrogen receptor-positive (ER+), HER2-negative, locally advanced/metastatic BC (LA/mBC)
Hope S. Rugo
Oncology | Estrogen Receptor Positive Breast Cancer

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11:00 AM
Duration 90mins Berlin, Germany
Reshaping the treatment of lung cancer together: Evolving options, changing perspectives
Solange Peters, Martin Reck, Luis Paz-Ares, Nicoline Ehrhardt
Oncology | Lung Cancer

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12:50 PM
Duration 5mins Hamburg Auditorium
Updated results from the phase III ALINA study of adjuvant alectinib vs chemotherapy (chemo) in patients (pts) with early-stage ALK+ non-small cell lung cancer (NSCLC)
Agata Higgerson, Andres Cardona, Astrid Scalori, Benjamin Solomon, Dae Ho Lee, FABRICE BARLESI, FILIPPO DE MARINIS, Hidehito Horinouchi, Igor Bondarenko, Jin Seok Ahn, Jong-Seok Lee, Makoto Nishio, Maria Rita Migliorino, Maximilian Hochmair, Rafał Dziadziuszko, Tingting Xu, Virginia McNally, Weimin Mao, Wenzhao Zhong, Yi-Long Wu
Oncology | Non-Small Cell Lung Cancer

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04:30 PM
Duration 90mins Berlin, Germany
Advancing Healthcare: Pioneering Efforts to Give Patients a Future in the Fight Against Gastrointestinal Cancers
Richard Finn, Manon Allaire, Frank Sinicrope, Anke Reinacher-Schick
Oncology | Gastrointestinal Cancer

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