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Gynecology

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Jan 30 / Roche
Reference range for Elecsys sFlt-1/PlGF ratio in a diverse U.S population
The sFlt-1/PlGF ratio test is used for the clinical prediction of preeclampsia in many countries worldwide but has not been widely adopted in the US. This study aimed to determine the reference range for the Roche Elecsys sFlt-1/PlGF ratio (electrochemiluminescent immunoassays) in a racially and ethnically diverse healthy US population of pregnant women at 23+0 - 34+6 gestational weeks.

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Nov 18 / Roche
Cost Consequence Analysis of Using the Elecsys Anti-Müllerian Hormone Plus Immunoassay as Part of Polycystic Ovary Syndrome Assessment in the United Kingdom
Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder amongst women. Diagnosis is based on the Rotterdam criteria, which requires at least two of the following criteria to be met: oligo-anovulation, clinical/biochemical hyperandrogenism and polycystic ovarian morphology (PCOM). PCOM detection has previously relied on transvaginal ultrasound, which is limited by diagnostic performance, accessibility and inter- and intra-operator variability. Anti-Müllerian hormone (AMH) testing is a new recommended alternative. This health economic study assessed the impact of using the Elecsys® AMH Plus immunoassay to detect PCOM for the diagnosis of PCOS in the United Kingdom.

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Oct 23 / Roche
Anti-Müllerian hormone to determine polycystic ovarian morphology: a sub-analysis of the APHRODITE study in an Asian population
An exploratory analysis of a cutoff for anti-Müllerian hormone (AMH) to identify PCOM with high sensitivity in Asian and Japanese women with PCOS phenotype A (the only phenotype diagnosed as PCOS in Japan).
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