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Inflammatory Bowel Disease

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Feb 25 / Roche
New frontiers in inflammatory bowel disease TL1A inhibition – from mode of action to clinical application
This symposium discussed how the current unmet medical need in IBD needs and how anti-TL1A therapies have the potential to address that need highlighting data from recent trials and a overview of the proposed mechanism of action of TL1A.

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Feb 22 / Roche and Genentech
Treatment with RO7790121 induces and maintains histologic and histologic-endoscopic improvement and remission in moderately to severely active Ulcerative Colitis - Results from TUSCANY-2
Histologic and endoscopic improvement and remission data from the TUSCANY-2 trial. This was a randomised, double-blind, placebo-controlled, dose-ranging Phase IIb study of RO7790121, an antibody against tumour necrosis factor like ligand 1A (anti-TL1A) in adults with moderately to severely active ulcerative colitis.

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Feb 21 / Roche and Genentech
RO7790121 shows early and rapid symptomatic remission in the treatment of moderately to severely active Ulcerative Colitis - Findings from the phase 2b TUSCANY-2 trial
Data from post-hoc analyses of patient-reported outcomes (PROs) from the TUSCANY-2 trial. This was a randomised, double-blind, placebo-controlled, dose-ranging Phase IIb study of RO7790121, an antibody against tumour necrosis factor like ligand 1A (anti-TL1A) in adults with moderately to severely active ulcerative colitis.
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May 3 - May 6, 2025 / San Diego, USA / Virtual (Hybrid)
DDW 2025
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