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Relapsed refractory multiple myeloma

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Dec 9 / Roche and Genentech
Biomarker correlates and clinical activity of cevostamab in patients with triple-class refractory multiple myeloma who have received >=1 prior B-cell maturation antigen-targeted bispecific antibody: results from the Phase I/II CAMMA 2 study
CAMMA 2 is a Phase I/II study of cevostamab monotherapy in patients with triple-class refractory multiple myeloma, who have received prior B-cell maturation antigen-targeted bispecific antibodies. Initial results and an exploratory analysis of baseline patient and tumor-related factors are presented.

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Dec 9 / Roche and Genentech
Cevostamab in Patients with Heavily Pretreated Relapsed/Refractory Multiple Myeloma: Updated Results from an Ongoing Phase I Study Demonstrate Clinically Meaningful Activity and Manageable Safety and Inform the Doses and Regimen for Combination Studies
GO39775 is an ongoing Phase I dose-escalation and dose-expansion study of cevostamab monotherapy in patients with heavily pre-treated relapsed/refractory multiple myeloma. This abstract reports the updated efficacy and safety data from patients who received cevostamab once every 3 weeks at the 160mg target-dose level.

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