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Home Neuroscience AAIC 2026
Roche and Genentech at

AAIC 2026

July 12 - July 15
London, United Kingdom / Virtual (Hybrid)
aaic.alz.org
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Medical Materials
Agenda
Coming soon
06:30 AM
Duration 60mins London, United Kingdom
Expanding clinical trial access to underrepresented populations in the US: Findings from the Alzheimer’s disease pre-screener study
Luisa Guglielmini, Irma Kurniawan, Tamiko MaGee-Rodgers, Justin Ford, Mia Chester, Theo Christofides, Enrique Gaspar, Kelly Coultes, Christopher Lane, Lisa Squassante, Nicola Maiorano, Julian Tillmann, Rosanna Tortelli, Ruth Croney
Neuroscience | Alzheimer Disease

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Duration 60mins London, United Kingdom
Elecsys cerebrospinal fluid biomarker ratio concordance with amyloid-positron emission tomography in a Chinese population
Jing Yuan, Tianxing Ji, Shengdi Chen, Xuefeng Wang, Jing Dai, Nan Zhang, Huifang Shang, Bei Cai, Jiehao Zhao, Zhiyin Lou, Yang Lu, Qinyong Ye, Ping Gao, Dongsheng Fan, Ning Wang, Pengcheng Ran, Qiman Yin, Yim Yung, Ling Qui, Jun Liu, Zhenxin Zhang
Neuroscience | Alzheimer Disease

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Duration 60mins London, United Kingdom
Elecsys pTau181 Plasma Immunoassay Performance Against Centiloid-Based Amyloid Classification Across Clinical Stages
Sayuri Hortsch, Myrto Andreadou, Imke Kirste, Dag Asrsland, Anna D. Burke, Jonathan Liss, Craig W. Ritchie, Kristian S. Frederiksen, Marc Suarez-Calvert, David Watson, Christopher Rowe
Neuroscience | Alzheimer Disease

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Duration 60mins London, United Kingdom
Evaluating the Elecsys in vitro diagnostic pTau217 plasma assay for the detection of amyloid pathology in primary and secondary care settings
Annunziata Di Domenico, Sayuri Hortsch, David Caley, Niels Borlinghaus, Kaj Blennow, Oskar Hansson, Marc Suarez-Calvert, Craig W. Ritchie, Nicholas J. Ashton, Marisa Denkinger, Christopher C. Rowe, Ming Lu, Sameera R. Wijayawardana, Sebastian Palmqvist
Neuroscience | Alzheimer Disease

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08:00 AM
Duration 90mins London, United Kingdom, Room N10
External controls vs. observed placebo: how close can we get? GRADUATE I and II results
Paul Delmar
Neuroscience | Alzheimer Disease

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06:30 AM
Duration 60mins London, United Kingdom
Investigating the Role of the NLRP3 Inflammasome in the Pathogenesis of Alzheimer’s Disease
Gennaro Pagano, Eva Mracsko, Eric Prinssen, Bastian Zinnhardt, Venissa Machado, Senthilvelrajan Kaniyappan, Stanislaw Adaszewski, Livia Takacs, Luka Kulic, Nicoletta Milani Muelhardt, Geoffrey A. Kerchner
Neuroscience | Alzheimer Disease

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01:00 PM
Duration 90mins London, United Kingdom, Room S8
Long-term safety and amyloid removal with trontinemab: interim data from the open-label extension of the Phase Ib/IIa Brainshuttle™ AD study
Luka Kulic
Neuroscience | Alzheimer Disease

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Duration 90mins London, United Kingdom, Room S8
PrevenTRON: Rationale and design of a Phase III trial of trontinemab in cognitively unimpaired individuals with biomarkers of Alzheimer’s disease at high risk of clinical decline
Janice Smith
Neuroscience | Alzheimer Disease

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Duration 90mins London, United Kingdom, Room S8
Simulation of amyloid clearance in Phase III studies with trontinemab in early symptomatic Alzheimer’s disease
Joao Abrantes
Neuroscience | Alzheimer Disease

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Duration 90mins London, United Kingdom, Room S8
Interim long-term biomarker results from the trontinemab open-label extension of the Phase Ib/IIa Brainshuttle™ AD study
Gregory Klein
Neuroscience | Alzheimer Disease

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Duration 90mins London, United Kingdom, Room N11A
The role of NLRP3 in Alzheimer’s disease: ​Reverse translational data from the Phase III GRADUATE trials
Gennaro Pagano
Neuroscience | Alzheimer Disease

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06:30 AM
Duration 60mins London, United Kingdom
Mental health conditions in spouses of people lliving with Alzheimer’s disease: a longitudinal US claims data analysis
Lars Kamber, Michelle Johnson, Valerie Crowell, Soeren Mattke, Richard Houghton
Neuroscience | Alzheimer Disease

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Duration 60mins London, United Kingdom
Sample stability for a new pTau181 plasma assay: implications for rule-out testing for Alzheimer’s disease in routine clinical practice
Sabine Wizemann, Carolin Kurz, Sophia Leonhardt, Anna Hufnagel, Heike Deutelmoser, Patrick Menzel, Robert Perneczky
Neuroscience | Alzheimer Disease

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Duration 60mins London, United Kingdom
A Low-Burden Cognitive Prescreening Protocol for Enhanced Diversity and Recruitment in Roche’s Alzheimer’s Disease Clinical Trials
Irma Kurniawan, Enrique Gaspar, Ruth Croney, Nicola Maiorano, Kelly Coultes, Christopher Lane, Lisa Squassante, Julian Tillmann, Rosanna Tortelli
Neuroscience | Alzheimer Disease

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01:00 PM
Duration 10mins London, United Kingdom, Room S8
Rule out performance of a plasma pTau181 (pT181p) assay at established cutoffs in subgroups across a large, diverse, cognitively impaired population
Sayuri Hortsch
Neuroscience | Agitation Alzheimer Disease

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Duration 90mins London, United Kingdom, Room Victoria 5/6
Tau pathology interferes with amyloid removal by gantenerumab
Matteo Tonietto
Neuroscience | Alzheimer Disease

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