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ESMO Asia 2024

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Dec 7 / Roche and Genentech
Whole exome sequencing (WES) analyses from IMpower133 and 6-year (y) overall survival (OS) from IMbrella A in patients (pts) with extensive-stage small cell lung cancer (ES-SCLC) treated with atezolizumab (atezo)
The Phase III IMbrella A study (NCT03148418; single-arm extension of IMpower133 [NCT02763579]) provided the first report of exploratory 5-year OS rate for 1L cancer immunotherapy (atezolizumab in combination with carboplatin plus etoposide) in patients with ES-SCLC. This poster reports exploratory analyses of the updated time-to-event data from patients who rolled over to IMbrella A, alongside the association of whole exome sequencing genomic alterations with OS in patients who were enrolled in IMpower133.

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Dec 7 / Roche and Genentech
Resistance mechanisms and efficacy of first-line (1L) alectinib in patients with ALK-rearranged non-small cell lung cancer: second interim analysis of ALCURE
Second interim analysis from the real-world ALCURE study exploring resistance mechanisms to first-line alectinib, prognostic factors of the efficacy of alectinib and optimal treatment sequences in Japanese patients with advanced ALK+ NSCLC.

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Dec 7 / Roche and Genentech
SKYSCRAPER-02C: phase 3 study of atezolizumab + carboplatin + etoposide (CE) with or without tiragolumab in patients with untreated extensive-stage small cell lung cancer (ES-SCLC) in China
Efficacy and safety of atezolizumab + carboplatin + etoposide with or without tiragolumab in patients with untreated extensive-stage small cell lung cancer in China from the phase 3 SKYSCRAPER-02C study.
04:00 AM
Duration 90mins Singapore, Republic of Singapore
Patient-centricity in Action: Innovating for Today and the Future in Lung and Liver Cancers
Prof. Toh Han Chong (Chair), Dr. David James Pinato, Prof. Sun Hui-Chuan, Assoc. Prof. Krittiya Korphaisarn, Mr. Eric Liu

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09:15 AM
Duration 5mins Hall 406
ALESIA 7-year update: alectinib vs crizotinib in Asian patients with treatment-naïve advanced ALK+ non-small cell lung cancer
Zhou C, Lu Y, Kim S-W, Reungwetwattana T, Zhou J, Zhang Y, He J, Yang J-J, Cheng Y, Lee S-H, Chang J, Fang J, Liu Z, Bu L, Qian L, Archer V, Zhou M, Zhang L

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09:50 AM
Duration 55mins Singapore, Republic of Singapore
Whole exome sequencing (WES) analyses from IMpower133 and 6-year (y) overall survival (OS) from IMbrella A in patients (pts) with extensive-stage small cell lung cancer (ES-SCLC) treated with atezolizumab (atezo)
Steven Kao, Martin Reck, Stephen V. Liu, Rafal Dziadziuszko, Maximilian Hochmair, Florian Huemer, Gilberto Castro, Junior, Reyes Bernab Caro, Se Hyun Kim, Dariusz Kowalski, Zoran Andric, Marcela Oancea, Monika Kaul, Huafei Li, Bradford Danner, Myung Chang Lee, Barzin Nabet, Shunichi Sugawara

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Duration 55mins Singapore, Republic of Singapore
Patient satisfaction and preference for atezolizumab subcutaneous by body mass index (BMI) or race (Asian vs non-Asian) from IMscin001 and IMscin002
Chewaskulyong B, Zvirbule Z, Lee KH, Yovanna Castro Sanchez A, Bustillos A, Herraez-Baranda L, Liu LX, Kim S-W

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Duration 55mins Singapore, Republic of Singapore
Resistance mechanisms and efficacy of first-line (1L) alectinib in patients with ALK-rearranged non-small cell lung cancer: second interim analysis of ALCURE
Atsuto Mouri, Takeshi Tsuda, Masahide Oki, Eiki Ichihara, Hiroshi Tanaka, Koichi Azuma, Ryo Arai, Shoichi Kuyama, Hiroaki Akamatsu, Kohei Otsubo, Hitomi Ajimizu, Marie Matsumoto, Yosuke Seto, Ken Uchibori, Hidetoshi Hayashi, Eisaku Miyauchi, Naoki Ishizuka, Yusuke Kajihara, Yuki Nakagawa, Ryohei Katayama

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Duration 55mins Singapore, Republic of Singapore
SKYSCRAPER-02C: phase 3 study of atezolizumab + carboplatin + etoposide (CE) with or without tiragolumab in patients with untreated extensive-stage small cell lung cancer (ES-SCLC) in China
Shun Lu, Jian Fang, Yan Yu, Yun Fan, Xiaorong Dong, Haiyan Wang, Chanjuan Lin, Li Zhang, Raymond Meng

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