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AASLD Liver meeting 2024

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03:00 PM
Duration 9hrs San Diago, CA
Outcomes of nucleos(t)ide analogue discontinuation following finite xalnesiran-based therapy in chronic hepatitis B: 48 week follow-up results from Piranga, a phase 2, randomized, controlled, adaptive, open-label platform study
Jinlin Hou, Qing Xie, Wenhong Zhang, Luis Enrique Morano Amado, Sheng-Shun Yang, Jidong Jia, Cheng-Yuan Peng, Wei-Wen Su, Jia-Horng Kao, Man-Fung Yuen, Tarik Asselah, Tawesak Tanwandee, Xieer Liang, Maria Teresa Catanese, Ethan Chen, Cong Cheng, Farouk Chughlay, Sudip Das, Katerina Glavini, Nelson Guerreiro, Yan Huang, Priyanka Kakrana, Rémi Kazma, Avinash Patil, Ruchi Upmanyu, Cynthia Wat, Edward Gane
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Duration 9hrs San Diago, CA
Pharmacokinetic/pharmacodynamic modelling of RG6084 effects on hepatitis B surface antigen and alanine transaminase to inform Phase 2 dosing regimen selection
Sijie Lu, Sylvie Retout, Vedran Pavlovic, Greg Hooper, Gemma Attley, Annabelle Lemenuel-Diot
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03:00 PM
Duration 9hrs San Diago, CA
Factors associated with type of first-line treatment received for unresectable hepatocellular carcinoma in the era of immunotherapy
Cheng S, To TM, Schuldt R, Tan A
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03:00 PM
Duration 9hrs San Diago, CA
Efficacy and safety of xalnesiran in combination with the checkpoint inhibitor PD-L1 LNA in virologically suppressed participants with chronic hepatitis B: results from the Piranga phase 2, randomized, controlled, adaptive, open-label platform study
Karen Doucette, Deian Jelev, Jia-Horng Kao, Luis Enrique Morano Amado, Kosh Agarwal, Tarik Asselah, Anchalee Avihingsanon, Rozalina Balabanska, Wan-Long Chuang, Apinya Leerapun, Tien Huey Lim, Young-Suk Lim, Wei-Wen Su, Sheng-Shun Yang, Ed Gane, Gemma Attley, Maria Teresa Catanese, Farouk Chughlay, Anna Maria Geretti, Gregory Hooper, Rémi Kazma, Yukun Liang, Sijie Lu, Ruchi Upmanyu, Jeffrey Xu, Wen Zhang, Man-Fung Yuen
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Duration 9hrs San Diago, CA
A novel mechanistic viral dynamics modeling (MVDM) framework to characterize and predict the effect of combination therapies in chronic hepatitis B: modeling of the Piranga phase 2, randomized, controlled, adaptive, open-label platform study
Annabelle Lemenuel-Diot, Selma El Messaoudi, Jeremie Guedj, Sylvie Retout, Franziska Schaedeli-Stark, Amine Ait-Ali, Nelson Guerreiro, Sijie Lu, Farouk Chughlay, Claire McGeown, Rémi Kazma
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