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Nov 6 / Roche and Genentech
Inhibition of IL-6 Receptor Signaling with Satralizumab▼ in Thyroid Eye Disease: Phase 3 SatraGO-1 and SatraGO-2 Trial Design
Thyroid eye disease (TED) is a rare, autoimmune, inflammatory ocular disorder that is potentially sight-threatening, disfiguring, and debilitating. This presentation describes the rationale and design of the Phase 3 SatraGO-1 and SatraGO-2 trials evaluating the efficacy and safety of satralizumab▼, a humanized monoclonal antibody developed using antibody recycling technology to target the IL-6 receptor pathway, in participants with active and inactive TED.